Anti-endothelial cell antibody rich sera from rheumatic heart disease patients induces proinflammatory phenotype and methylation alteration in endothelial cells

Rheumatic heart disease (RHD) is a major cause of cardiovascular morbidity and mortality in developing nations like India. RHD commonly affects the mitral valve which is lined by a single layer of endothelial cells (ECs). The role of ECs in mitral valve damage during RHD is not well elucidated. In h...

Descripción completa

Detalles Bibliográficos
Autores principales: Rastogi, Mukul, Sarkar, Subendu, Makol, Ankita, Sandip Singh, Rana, Saikia, Uma Nahar, Banerjee, Dibyajyoti, Chopra, Seema, Chakraborti, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176156/
https://www.ncbi.nlm.nih.gov/pubmed/30320192
http://dx.doi.org/10.1016/j.gendis.2018.02.002

Ejemplares similares

Ejemplares similares