Cargando…
CMHX008, a PPARγ partial agonist, enhances insulin sensitivity with minor influences on bone loss
Traditional thiazolidinediones (TZDs), such as rosiglitazone, are peroxisome proliferator-activated receptor γ (PPARγ) potent agonists that can be used to treat type 2 diabetes but carry unwanted effects, including increased risk for fracture. The present work aimed to compare the insulin-sensitizin...
Autores principales: | Hou, Yi, Cao, Xuemei, Hu, Xiangnan, Li, Xinyu, Shi, Xiaoqin, Wang, Hongying, Peng, Chuan, Li, Jiayu, Li, Jibin, Li, Qifu, Wu, Chaodong, Xiao, Xiaoqiu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176219/ https://www.ncbi.nlm.nih.gov/pubmed/30320193 http://dx.doi.org/10.1016/j.gendis.2018.05.004 |
Ejemplares similares
-
CMHX008, a Novel Peroxisome Proliferator-Activated Receptor γ Partial Agonist, Enhances Insulin Sensitivity In Vitro and In Vivo
por: Ming, Yue, et al.
Publicado: (2014) -
Ectopic Overexpression of PPARγ2 in the Heart Determines Differences in Hypertrophic Cardiomyopathy After Treatment With Different Thiazolidinediones in a Mouse Model of Diabetes
por: Cao, Xuemei, et al.
Publicado: (2021) -
Hippocampal overexpression of TREM2 ameliorates high fat diet induced cognitive impairment and modulates phenotypic polarization of the microglia
por: Wu, Min, et al.
Publicado: (2020) -
PPAR-γ Partial Agonists in Disease-Fate Decision with Special Reference to Cancer
por: Ballav, Sangeeta, et al.
Publicado: (2022) -
Scaffold-Based Pan-Agonist Design for the PPARα, PPARβ and PPARγ Receptors
por: Zhang, Li-Song, et al.
Publicado: (2012)