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Outcome Measures for Central Nervous System Evaluation in Myotonic Dystrophy Type 1 May Be Confounded by Deficits in Motor Function or Insight
Background: Central nervous system involvement in myotonic dystrophy type 1 (DM1) is associated with cognitive deficits, impaired social performance and excessive somnolence, which greatly impact quality of life. With the advent of clinical trials in DM1, there is a pressing need to identify outcome...
Autores principales: | Hamilton, Mark J., McLean, John, Cumming, Sarah, Ballantyne, Bob, McGhie, Josephine, Jampana, Ravi, Longman, Cheryl, Evans, Jonathan J., Monckton, Darren G., Farrugia, Maria Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176265/ https://www.ncbi.nlm.nih.gov/pubmed/30333784 http://dx.doi.org/10.3389/fneur.2018.00780 |
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