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2(3) Full Factorial Model for Particle Size Optimization of Methotrexate Loaded Chitosan Nanocarriers: A Design of Experiments (DoE) Approach

PURPOSE: To build and inquire a statistically significant mathematical model for manufacturing methotrexate loaded chitosan nanoparticles (CsNP) of desired particle size. The study was also performed to evaluate the effect of formulation variables in the explored design space. METHOD: Ionotropic gel...

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Detalles Bibliográficos
Autores principales: Teja, S. P. Surya, Damodharan, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176313/
https://www.ncbi.nlm.nih.gov/pubmed/30356374
http://dx.doi.org/10.1155/2018/7834159

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