The Ethnic-Specific Spectrum of Germline Nucleotide Variants in DNA Damage Response and Repair Genes in Hereditary Breast and Ovarian Cancer Patients of Tatar Descent

The Russian population consists of more than 100 ethnic groups, presenting a unique opportunity for the identification of hereditary pathogenic mutations. To gain insight into the landscape of heredity pathogenic variants, we employed targeted next-generation sequencing to analyze the germline mutat...

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Detalles Bibliográficos
Autores principales: Brovkina, Olga I., Shigapova, Leila, Chudakova, Daria A., Gordiev, Marat G., Enikeev, Rafael F., Druzhkov, Maxim O., Khodyrev, Dmitriy S., Shagimardanova, Elena I., Nikitin, Alexey G., Gusev, Oleg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176317/
https://www.ncbi.nlm.nih.gov/pubmed/30333958
http://dx.doi.org/10.3389/fonc.2018.00421

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