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Estimating Everyday Neuropsychological Functioning in Multiple Sclerosis: Reliability and Validity of the Greek Multiple Sclerosis Neuropsychological Questionnaire

The Multiple Sclerosis Neuropsychological Questionnaire is a brief screening questionnaire for the assessment of everyday neuropsychological competence of patients with Multiple Sclerosis. The aim of the present study was to examine psychometric properties of the Greek version of the instrument. One...

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Autores principales: Konstantinopoulou, Eleni, Ioannidis, Panagiotis, Bakirtzis, Christos, Giantzi, Virginia, Afrantou, Theodora, Parissis, Dimitrios, Messinis, Lambros, Nasios, Grigorios, Grigoriadis, Nikolaos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176322/
https://www.ncbi.nlm.nih.gov/pubmed/30356376
http://dx.doi.org/10.1155/2018/6301535
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author Konstantinopoulou, Eleni
Ioannidis, Panagiotis
Bakirtzis, Christos
Giantzi, Virginia
Afrantou, Theodora
Parissis, Dimitrios
Messinis, Lambros
Nasios, Grigorios
Grigoriadis, Nikolaos
author_facet Konstantinopoulou, Eleni
Ioannidis, Panagiotis
Bakirtzis, Christos
Giantzi, Virginia
Afrantou, Theodora
Parissis, Dimitrios
Messinis, Lambros
Nasios, Grigorios
Grigoriadis, Nikolaos
author_sort Konstantinopoulou, Eleni
collection PubMed
description The Multiple Sclerosis Neuropsychological Questionnaire is a brief screening questionnaire for the assessment of everyday neuropsychological competence of patients with Multiple Sclerosis. The aim of the present study was to examine psychometric properties of the Greek version of the instrument. One hundred and three MS patients and 60 informants participated in the present study and completed the questionnaire. From the initial patient sample, 51 participants completed broadly used neuropsychological tests and measures estimating cognitive failures and depression. Moreover, after a six-month interval the MSNQ was administered to 58 patients from the initial sample in order to explore test-retest reliability. Cronbach's α was 0.92 and 0.93 for patient and informant forms, respectively. The patient form was correlated significantly with measures of cognitive failures and depression. Low correlations were found between the informant form and performance on cognitive tests. In regard to the patient form, significant correlation was observed between repeated administrations and, psychometrically, the three-factor structure was preferable than the one-factor structure. The present study confirms the already established pattern of correlations among the two MSNQ forms, neuropsychological test performance and depression measurements. Additional research is needed in order to define a cut-off score for the MSNQ-I providing further information about the diagnostic interpretability of the instrument.
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spelling pubmed-61763222018-10-23 Estimating Everyday Neuropsychological Functioning in Multiple Sclerosis: Reliability and Validity of the Greek Multiple Sclerosis Neuropsychological Questionnaire Konstantinopoulou, Eleni Ioannidis, Panagiotis Bakirtzis, Christos Giantzi, Virginia Afrantou, Theodora Parissis, Dimitrios Messinis, Lambros Nasios, Grigorios Grigoriadis, Nikolaos Mult Scler Int Research Article The Multiple Sclerosis Neuropsychological Questionnaire is a brief screening questionnaire for the assessment of everyday neuropsychological competence of patients with Multiple Sclerosis. The aim of the present study was to examine psychometric properties of the Greek version of the instrument. One hundred and three MS patients and 60 informants participated in the present study and completed the questionnaire. From the initial patient sample, 51 participants completed broadly used neuropsychological tests and measures estimating cognitive failures and depression. Moreover, after a six-month interval the MSNQ was administered to 58 patients from the initial sample in order to explore test-retest reliability. Cronbach's α was 0.92 and 0.93 for patient and informant forms, respectively. The patient form was correlated significantly with measures of cognitive failures and depression. Low correlations were found between the informant form and performance on cognitive tests. In regard to the patient form, significant correlation was observed between repeated administrations and, psychometrically, the three-factor structure was preferable than the one-factor structure. The present study confirms the already established pattern of correlations among the two MSNQ forms, neuropsychological test performance and depression measurements. Additional research is needed in order to define a cut-off score for the MSNQ-I providing further information about the diagnostic interpretability of the instrument. Hindawi 2018-09-25 /pmc/articles/PMC6176322/ /pubmed/30356376 http://dx.doi.org/10.1155/2018/6301535 Text en Copyright © 2018 Eleni Konstantinopoulou et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Konstantinopoulou, Eleni
Ioannidis, Panagiotis
Bakirtzis, Christos
Giantzi, Virginia
Afrantou, Theodora
Parissis, Dimitrios
Messinis, Lambros
Nasios, Grigorios
Grigoriadis, Nikolaos
Estimating Everyday Neuropsychological Functioning in Multiple Sclerosis: Reliability and Validity of the Greek Multiple Sclerosis Neuropsychological Questionnaire
title Estimating Everyday Neuropsychological Functioning in Multiple Sclerosis: Reliability and Validity of the Greek Multiple Sclerosis Neuropsychological Questionnaire
title_full Estimating Everyday Neuropsychological Functioning in Multiple Sclerosis: Reliability and Validity of the Greek Multiple Sclerosis Neuropsychological Questionnaire
title_fullStr Estimating Everyday Neuropsychological Functioning in Multiple Sclerosis: Reliability and Validity of the Greek Multiple Sclerosis Neuropsychological Questionnaire
title_full_unstemmed Estimating Everyday Neuropsychological Functioning in Multiple Sclerosis: Reliability and Validity of the Greek Multiple Sclerosis Neuropsychological Questionnaire
title_short Estimating Everyday Neuropsychological Functioning in Multiple Sclerosis: Reliability and Validity of the Greek Multiple Sclerosis Neuropsychological Questionnaire
title_sort estimating everyday neuropsychological functioning in multiple sclerosis: reliability and validity of the greek multiple sclerosis neuropsychological questionnaire
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176322/
https://www.ncbi.nlm.nih.gov/pubmed/30356376
http://dx.doi.org/10.1155/2018/6301535
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