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Investigation of the outcome of patients with hip fractures using vitamin D3

Hip fracture is one of the important health problems of human societies. The aim of this study was to investigate the outcome of patients with this fracture using vitamin D3. This double-blind clinical trial was performed on 100 patients with hip fractures who referred to Valiasr Hospital. All speci...

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Autores principales: Behrouzi, Ahmadreza, Hejazi, Hojat, Kamali, Alireza, Hadi, Hoseinali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176387/
https://www.ncbi.nlm.nih.gov/pubmed/30344973
http://dx.doi.org/10.4081/ejtm.2018.7372
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author Behrouzi, Ahmadreza
Hejazi, Hojat
Kamali, Alireza
Hadi, Hoseinali
author_facet Behrouzi, Ahmadreza
Hejazi, Hojat
Kamali, Alireza
Hadi, Hoseinali
author_sort Behrouzi, Ahmadreza
collection PubMed
description Hip fracture is one of the important health problems of human societies. The aim of this study was to investigate the outcome of patients with this fracture using vitamin D3. This double-blind clinical trial was performed on 100 patients with hip fractures who referred to Valiasr Hospital. All specimens were evaluated for vitamin D3. Group A have had vitamin D3 in the normal range and received a dose of 50,000 vitamin D3 as blouse. Group B included individuals with hip fractures that did not have normal vitamin D3 levels. In this group, individuals received a dose of 50,000 units vitamin D3 in the form of muscular blouse, and then 50,000 units of vitamin D3 were given orally each week up to 12 weeks after surgery. After surgery, both groups were examined clinically and radiologically for ulcer and fracture healing. Moreover, mortality was checked 2 weeks after surgery and each month until healing. There was no significant difference in radiographic examination in the two groups in the term of adhesion and fracture union (P <0.05). The formation of the union in the clinical examination 4 and 8 weeks after treatment in two groups showed significant difference. The formation of union in clinical presentation 4 weeks and 8 weeks after treatment in two groups showed significant difference (P = 0.005; P = 0.036). The results showed that a group with low vitamin D, but with supplementation, had more fracture union after 4 and 8 weeks after starting treatment. Vitamin D supplementation could improve patients' condition 4 and 8 weeks after treatment.
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spelling pubmed-61763872018-10-19 Investigation of the outcome of patients with hip fractures using vitamin D3 Behrouzi, Ahmadreza Hejazi, Hojat Kamali, Alireza Hadi, Hoseinali Eur J Transl Myol Vitamin D3 in hip fractures Hip fracture is one of the important health problems of human societies. The aim of this study was to investigate the outcome of patients with this fracture using vitamin D3. This double-blind clinical trial was performed on 100 patients with hip fractures who referred to Valiasr Hospital. All specimens were evaluated for vitamin D3. Group A have had vitamin D3 in the normal range and received a dose of 50,000 vitamin D3 as blouse. Group B included individuals with hip fractures that did not have normal vitamin D3 levels. In this group, individuals received a dose of 50,000 units vitamin D3 in the form of muscular blouse, and then 50,000 units of vitamin D3 were given orally each week up to 12 weeks after surgery. After surgery, both groups were examined clinically and radiologically for ulcer and fracture healing. Moreover, mortality was checked 2 weeks after surgery and each month until healing. There was no significant difference in radiographic examination in the two groups in the term of adhesion and fracture union (P <0.05). The formation of the union in the clinical examination 4 and 8 weeks after treatment in two groups showed significant difference. The formation of union in clinical presentation 4 weeks and 8 weeks after treatment in two groups showed significant difference (P = 0.005; P = 0.036). The results showed that a group with low vitamin D, but with supplementation, had more fracture union after 4 and 8 weeks after starting treatment. Vitamin D supplementation could improve patients' condition 4 and 8 weeks after treatment. PAGEPress Publications, Pavia, Italy 2018-07-27 /pmc/articles/PMC6176387/ /pubmed/30344973 http://dx.doi.org/10.4081/ejtm.2018.7372 Text en http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Vitamin D3 in hip fractures
Behrouzi, Ahmadreza
Hejazi, Hojat
Kamali, Alireza
Hadi, Hoseinali
Investigation of the outcome of patients with hip fractures using vitamin D3
title Investigation of the outcome of patients with hip fractures using vitamin D3
title_full Investigation of the outcome of patients with hip fractures using vitamin D3
title_fullStr Investigation of the outcome of patients with hip fractures using vitamin D3
title_full_unstemmed Investigation of the outcome of patients with hip fractures using vitamin D3
title_short Investigation of the outcome of patients with hip fractures using vitamin D3
title_sort investigation of the outcome of patients with hip fractures using vitamin d3
topic Vitamin D3 in hip fractures
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176387/
https://www.ncbi.nlm.nih.gov/pubmed/30344973
http://dx.doi.org/10.4081/ejtm.2018.7372
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