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Crizotinib induces apoptosis of lung cancer cells through JAK-STAT pathway

Effect of crizotinib on apoptosis of lung cancer cells was investigated. Human non-small cell lung adenocarcinoma H2228 cells were cultured in the presence of 0, 20, 40, 80, 160 and 320 nmol/l of crizotinib for 3 days, respectively. The inhibition rate of cell proliferation was measured by MTT assay...

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Detalles Bibliográficos
Autores principales:	Lu, Hongmin, Wu, Shibo, Chen, Huafei, Huang, Ying, Qiu, Guoqin, Liu, Lingxiang, Li, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176410/ https://www.ncbi.nlm.nih.gov/pubmed/30333870 http://dx.doi.org/10.3892/ol.2018.9387

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