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Using Machine Learning to Predict Synergistic Antimalarial Compound Combinations With Novel Structures

The parasite Plasmodium falciparum is the most lethal species of Plasmodium to cause serious malaria infection in humans, and with resistance developing rapidly novel treatment modalities are currently being sought, one of which being combinations of existing compounds. The discovery of combinations...

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Detalles Bibliográficos
Autores principales: Mason, Daniel J., Eastman, Richard T., Lewis, Richard P. I., Stott, Ian P., Guha, Rajarshi, Bender, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176478/
https://www.ncbi.nlm.nih.gov/pubmed/30333748
http://dx.doi.org/10.3389/fphar.2018.01096