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A molecular mechanism for calcium/synaptotagmin-triggered exocytosis
The regulated exocytotic release of neurotransmitter and hormones is accomplished by a complex protein machinery consisting in its core of SNARE proteins and the calcium sensor synaptotagmin-1. We propose a mechanism where the lipid membrane is intimately involved in coupling calcium sensing to rele...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176490/ https://www.ncbi.nlm.nih.gov/pubmed/30291360 http://dx.doi.org/10.1038/s41594-018-0130-9 |