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A molecular mechanism for calcium/synaptotagmin-triggered exocytosis

The regulated exocytotic release of neurotransmitter and hormones is accomplished by a complex protein machinery consisting in its core of SNARE proteins and the calcium sensor synaptotagmin-1. We propose a mechanism where the lipid membrane is intimately involved in coupling calcium sensing to rele...

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Detalles Bibliográficos
Autores principales:	Kiessling, Volker, Kreutzberger, Alex J.B., Liang, Binyong, Nyenhuis, Sarah B., Seelheim, Patrick, Castle, J. David, Cafiso, David S., Tamm, Lukas K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176490/ https://www.ncbi.nlm.nih.gov/pubmed/30291360 http://dx.doi.org/10.1038/s41594-018-0130-9

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