Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells

Intestinal epithelial cells (IECs) play a key role in regulating immune responses and controlling infection. However, the direct role of IECs in restricting pathogens remains incompletely understood. Here, we provide evidence that IL-22 primed intestinal organoids derived from healthy human induced...

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Detalles Bibliográficos
Autores principales: Forbester, Jessica L., Lees, Emily A., Goulding, David, Forrest, Sally, Yeung, Amy, Speak, Anneliese, Clare, Simon, Coomber, Eve L., Mukhopadhyay, Subhankar, Kraiczy, Judith, Schreiber, Fernanda, Lawley, Trevor D., Hancock, Robert E. W., Uhlig, Holm H., Zilbauer, Matthias, Powrie, Fiona, Dougan, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176607/
https://www.ncbi.nlm.nih.gov/pubmed/30217896
http://dx.doi.org/10.1073/pnas.1811866115

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