Microfluidic light-driven synthesis of tetracyclic molecular architectures

Herein we report an effective synthetic method for the direct assembly of highly functionalized tetracyclic pharmacophoric cores. Coumarins and chromones undergo diastereoselective [4 + 2] cycloaddition reactions with light-generated photoenol intermediates. The reactions occur by aid of a microflui...

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Detalles Bibliográficos
Autores principales: Mateos, Javier, Meneghini, Nicholas, Bonchio, Marcella, Marino, Nadia, Carofiglio, Tommaso, Companyó, Xavier, Dell’Amico, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176812/
https://www.ncbi.nlm.nih.gov/pubmed/30344766
http://dx.doi.org/10.3762/bjoc.14.219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176812/
https://www.ncbi.nlm.nih.gov/pubmed/30344766
http://dx.doi.org/10.3762/bjoc.14.219

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