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RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses

HIV-1 broadly neutralizing antibodies (bnAbs) are difficult to induce with vaccines but are generated in ∼50% of HIV-1-infected individuals. Understanding the molecular mechanisms of host control of bnAb induction is critical to vaccine design. Here, we performed a transcriptome analysis of blood mo...

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Detalles Bibliográficos
Autores principales: Bradley, Todd, Peppa, Dimitra, Pedroza-Pacheco, Isabela, Li, Dapeng, Cain, Derek W., Henao, Ricardo, Venkat, Vaishnavi, Hora, Bhavna, Chen, Yue, Vandergrift, Nathan A., Overman, R. Glenn, Edwards, R. Whitney, Woods, Chris W., Tomaras, Georgia D., Ferrari, Guido, Ginsburg, Geoffrey S., Connors, Mark, Cohen, Myron S., Moody, M. Anthony, Borrow, Persephone, Haynes, Barton F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176872/
https://www.ncbi.nlm.nih.gov/pubmed/30270043
http://dx.doi.org/10.1016/j.cell.2018.08.064