The Impact of NOD2 Variants on Fecal Microbiota in Crohn’s Disease and Controls Without Gastrointestinal Disease

BACKGROUND/AIMS: Current models of Crohn’s disease (CD) describe an inappropriate immune response to gut microbiota in genetically susceptible individuals. NOD2 variants are strongly associated with development of CD, and NOD2 is part of the innate immune response to bacteria. This study aimed to id...

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Detalles Bibliográficos
Autores principales: Kennedy, Nicholas A, Lamb, Christopher A, Berry, Susan H, Walker, Alan W, Mansfield, John, Parkes, Miles, Simpkins, Rachel, Tremelling, Mark, Nutland, Sarah, Parkhill, Julian, Probert, Chris, Hold, Georgina L, Lees, Charlie W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Research Articles–Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176884/
https://www.ncbi.nlm.nih.gov/pubmed/29462388
http://dx.doi.org/10.1093/ibd/izx061

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