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Chart review across EU5 in MM post-ASCT patients
AIM: To understand the current treatment patterns, clinical outcomes and healthcare resource utilization–associated costs for multiple myeloma patients, post autologous stem cell transplant (ASCT) across Europe. PATIENTS & METHODS: Medical records were used to abstract data for 337 multiple myel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176952/ https://www.ncbi.nlm.nih.gov/pubmed/30302236 http://dx.doi.org/10.2217/ijh-2018-0004 |
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author | Ashcroft, John Judge, Davneet Dhanasiri, Sujith Taylor-Stokes, Gavin Middleton, Chloe |
author_facet | Ashcroft, John Judge, Davneet Dhanasiri, Sujith Taylor-Stokes, Gavin Middleton, Chloe |
author_sort | Ashcroft, John |
collection | PubMed |
description | AIM: To understand the current treatment patterns, clinical outcomes and healthcare resource utilization–associated costs for multiple myeloma patients, post autologous stem cell transplant (ASCT) across Europe. PATIENTS & METHODS: Medical records were used to abstract data for 337 multiple myeloma patients who had received ASCT. RESULTS: Following ASCT, 7% received maintenance therapy prior to progression. Lenalidomide was the most frequently prescribed maintenance, second- and third-line therapy. Monthly resource use was considerably lower in patients who received maintenance therapy (€638.14 vs €1001.74). Median time to progression was longer for patients who had received maintenance therapy. CONCLUSION: The study highlights the diversity in current treatment patterns post-ASCT. Results suggest patients who receive maintenance therapy have a prolonged remission period, and as a result their associated healthcare resource utilization is spread across the treatment pathway. |
format | Online Article Text |
id | pubmed-6176952 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Future Medicine Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-61769522018-10-09 Chart review across EU5 in MM post-ASCT patients Ashcroft, John Judge, Davneet Dhanasiri, Sujith Taylor-Stokes, Gavin Middleton, Chloe Int J Hematol Oncol Research Article AIM: To understand the current treatment patterns, clinical outcomes and healthcare resource utilization–associated costs for multiple myeloma patients, post autologous stem cell transplant (ASCT) across Europe. PATIENTS & METHODS: Medical records were used to abstract data for 337 multiple myeloma patients who had received ASCT. RESULTS: Following ASCT, 7% received maintenance therapy prior to progression. Lenalidomide was the most frequently prescribed maintenance, second- and third-line therapy. Monthly resource use was considerably lower in patients who received maintenance therapy (€638.14 vs €1001.74). Median time to progression was longer for patients who had received maintenance therapy. CONCLUSION: The study highlights the diversity in current treatment patterns post-ASCT. Results suggest patients who receive maintenance therapy have a prolonged remission period, and as a result their associated healthcare resource utilization is spread across the treatment pathway. Future Medicine Ltd 2018-07-11 /pmc/articles/PMC6176952/ /pubmed/30302236 http://dx.doi.org/10.2217/ijh-2018-0004 Text en © 2018 Sujith Dhanasiri This work is licensed under a Creative Commons Attribution-NonCommercial NonDerivative 4.0 Unported License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Research Article Ashcroft, John Judge, Davneet Dhanasiri, Sujith Taylor-Stokes, Gavin Middleton, Chloe Chart review across EU5 in MM post-ASCT patients |
title | Chart review across EU5 in MM post-ASCT patients |
title_full | Chart review across EU5 in MM post-ASCT patients |
title_fullStr | Chart review across EU5 in MM post-ASCT patients |
title_full_unstemmed | Chart review across EU5 in MM post-ASCT patients |
title_short | Chart review across EU5 in MM post-ASCT patients |
title_sort | chart review across eu5 in mm post-asct patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176952/ https://www.ncbi.nlm.nih.gov/pubmed/30302236 http://dx.doi.org/10.2217/ijh-2018-0004 |
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