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Chart review across EU5 in MM post-ASCT patients

AIM: To understand the current treatment patterns, clinical outcomes and healthcare resource utilization–associated costs for multiple myeloma patients, post autologous stem cell transplant (ASCT) across Europe. PATIENTS & METHODS: Medical records were used to abstract data for 337 multiple myel...

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Autores principales: Ashcroft, John, Judge, Davneet, Dhanasiri, Sujith, Taylor-Stokes, Gavin, Middleton, Chloe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176952/
https://www.ncbi.nlm.nih.gov/pubmed/30302236
http://dx.doi.org/10.2217/ijh-2018-0004
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author Ashcroft, John
Judge, Davneet
Dhanasiri, Sujith
Taylor-Stokes, Gavin
Middleton, Chloe
author_facet Ashcroft, John
Judge, Davneet
Dhanasiri, Sujith
Taylor-Stokes, Gavin
Middleton, Chloe
author_sort Ashcroft, John
collection PubMed
description AIM: To understand the current treatment patterns, clinical outcomes and healthcare resource utilization–associated costs for multiple myeloma patients, post autologous stem cell transplant (ASCT) across Europe. PATIENTS & METHODS: Medical records were used to abstract data for 337 multiple myeloma patients who had received ASCT. RESULTS: Following ASCT, 7% received maintenance therapy prior to progression. Lenalidomide was the most frequently prescribed maintenance, second- and third-line therapy. Monthly resource use was considerably lower in patients who received maintenance therapy (€638.14 vs €1001.74). Median time to progression was longer for patients who had received maintenance therapy. CONCLUSION: The study highlights the diversity in current treatment patterns post-ASCT. Results suggest patients who receive maintenance therapy have a prolonged remission period, and as a result their associated healthcare resource utilization is spread across the treatment pathway.
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spelling pubmed-61769522018-10-09 Chart review across EU5 in MM post-ASCT patients Ashcroft, John Judge, Davneet Dhanasiri, Sujith Taylor-Stokes, Gavin Middleton, Chloe Int J Hematol Oncol Research Article AIM: To understand the current treatment patterns, clinical outcomes and healthcare resource utilization–associated costs for multiple myeloma patients, post autologous stem cell transplant (ASCT) across Europe. PATIENTS & METHODS: Medical records were used to abstract data for 337 multiple myeloma patients who had received ASCT. RESULTS: Following ASCT, 7% received maintenance therapy prior to progression. Lenalidomide was the most frequently prescribed maintenance, second- and third-line therapy. Monthly resource use was considerably lower in patients who received maintenance therapy (€638.14 vs €1001.74). Median time to progression was longer for patients who had received maintenance therapy. CONCLUSION: The study highlights the diversity in current treatment patterns post-ASCT. Results suggest patients who receive maintenance therapy have a prolonged remission period, and as a result their associated healthcare resource utilization is spread across the treatment pathway. Future Medicine Ltd 2018-07-11 /pmc/articles/PMC6176952/ /pubmed/30302236 http://dx.doi.org/10.2217/ijh-2018-0004 Text en © 2018 Sujith Dhanasiri This work is licensed under a Creative Commons Attribution-NonCommercial NonDerivative 4.0 Unported License (http://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Research Article
Ashcroft, John
Judge, Davneet
Dhanasiri, Sujith
Taylor-Stokes, Gavin
Middleton, Chloe
Chart review across EU5 in MM post-ASCT patients
title Chart review across EU5 in MM post-ASCT patients
title_full Chart review across EU5 in MM post-ASCT patients
title_fullStr Chart review across EU5 in MM post-ASCT patients
title_full_unstemmed Chart review across EU5 in MM post-ASCT patients
title_short Chart review across EU5 in MM post-ASCT patients
title_sort chart review across eu5 in mm post-asct patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176952/
https://www.ncbi.nlm.nih.gov/pubmed/30302236
http://dx.doi.org/10.2217/ijh-2018-0004
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