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Pgc-1α repression and high-fat diet induce age-related macular degeneration-like phenotypes in mice

Age-related macular degeneration (AMD) is the major cause of blindness in the elderly in developed countries and its prevalence is increasing with the aging population. AMD initially affects the retinal pigment epithelium (RPE) and gradually leads to secondary photoreceptor degeneration. Recent stud...

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Detalles Bibliográficos
Autores principales:	Zhang, Meng, Chu, Yi, Mowery, Joseph, Konkel, Brandon, Galli, Susana, Theos, Alexander C., Golestaneh, Nady
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176989/ https://www.ncbi.nlm.nih.gov/pubmed/29925537 http://dx.doi.org/10.1242/dmm.032698

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