Cargando…
Association between ibrutinib and mid-cavitary Takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced Takostubo’s cardiomyopathy
Takotsubo cardiomyopathy (TC) is a rare but increasingly recognized phenomenon, which can occur as a side effect of cancer treatment. We report an interesting case of a 53-year-old woman with non-small-cell lung cancer, who developed TC after chemotherapy with ibrutinib. Echocardiography revealed ma...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177044/ https://www.ncbi.nlm.nih.gov/pubmed/31020065 http://dx.doi.org/10.1093/ehjcr/ytx006 |
_version_ | 1783361794326134784 |
---|---|
author | Giza, Dana Elena Moudgil, Rohit Lopez-Mattei, Juan Kim, Peter Iliescu, Cezar |
author_facet | Giza, Dana Elena Moudgil, Rohit Lopez-Mattei, Juan Kim, Peter Iliescu, Cezar |
author_sort | Giza, Dana Elena |
collection | PubMed |
description | Takotsubo cardiomyopathy (TC) is a rare but increasingly recognized phenomenon, which can occur as a side effect of cancer treatment. We report an interesting case of a 53-year-old woman with non-small-cell lung cancer, who developed TC after chemotherapy with ibrutinib. Echocardiography revealed marked left ventricular dysfunction with apical hyperkinesis and mid-ventricular hypokinesia. Coronary angiogram was normal but did show mid-cavitary akinesis. To our knowledge, this is the first case of TC with ibrutinib. Therefore, TC remains a rare entity, and we present an elegant case of ibrutinib-mediated mid-cavitary Takotsubo cardiomyopathy with a literature review. |
format | Online Article Text |
id | pubmed-6177044 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61770442019-04-24 Association between ibrutinib and mid-cavitary Takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced Takostubo’s cardiomyopathy Giza, Dana Elena Moudgil, Rohit Lopez-Mattei, Juan Kim, Peter Iliescu, Cezar Eur Heart J Case Rep Case Reports Takotsubo cardiomyopathy (TC) is a rare but increasingly recognized phenomenon, which can occur as a side effect of cancer treatment. We report an interesting case of a 53-year-old woman with non-small-cell lung cancer, who developed TC after chemotherapy with ibrutinib. Echocardiography revealed marked left ventricular dysfunction with apical hyperkinesis and mid-ventricular hypokinesia. Coronary angiogram was normal but did show mid-cavitary akinesis. To our knowledge, this is the first case of TC with ibrutinib. Therefore, TC remains a rare entity, and we present an elegant case of ibrutinib-mediated mid-cavitary Takotsubo cardiomyopathy with a literature review. Oxford University Press 2017-11-02 /pmc/articles/PMC6177044/ /pubmed/31020065 http://dx.doi.org/10.1093/ehjcr/ytx006 Text en © The Author 2017. Published by Oxford University Press on behalf of the European Society of Cardiology http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Reports Giza, Dana Elena Moudgil, Rohit Lopez-Mattei, Juan Kim, Peter Iliescu, Cezar Association between ibrutinib and mid-cavitary Takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced Takostubo’s cardiomyopathy |
title | Association between ibrutinib and mid-cavitary Takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced Takostubo’s cardiomyopathy |
title_full | Association between ibrutinib and mid-cavitary Takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced Takostubo’s cardiomyopathy |
title_fullStr | Association between ibrutinib and mid-cavitary Takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced Takostubo’s cardiomyopathy |
title_full_unstemmed | Association between ibrutinib and mid-cavitary Takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced Takostubo’s cardiomyopathy |
title_short | Association between ibrutinib and mid-cavitary Takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced Takostubo’s cardiomyopathy |
title_sort | association between ibrutinib and mid-cavitary takotsubo cardiomyopathy: a case report and a review of chemotherapy-induced takostubo’s cardiomyopathy |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177044/ https://www.ncbi.nlm.nih.gov/pubmed/31020065 http://dx.doi.org/10.1093/ehjcr/ytx006 |
work_keys_str_mv | AT gizadanaelena associationbetweenibrutinibandmidcavitarytakotsubocardiomyopathyacasereportandareviewofchemotherapyinducedtakostuboscardiomyopathy AT moudgilrohit associationbetweenibrutinibandmidcavitarytakotsubocardiomyopathyacasereportandareviewofchemotherapyinducedtakostuboscardiomyopathy AT lopezmatteijuan associationbetweenibrutinibandmidcavitarytakotsubocardiomyopathyacasereportandareviewofchemotherapyinducedtakostuboscardiomyopathy AT kimpeter associationbetweenibrutinibandmidcavitarytakotsubocardiomyopathyacasereportandareviewofchemotherapyinducedtakostuboscardiomyopathy AT iliescucezar associationbetweenibrutinibandmidcavitarytakotsubocardiomyopathyacasereportandareviewofchemotherapyinducedtakostuboscardiomyopathy |