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Melioidosis: an unusual cause of infective endocarditis: a case report
INTRODUCTION: As a causal organism in infective endocarditis, Burkholderia pseudomallei is rare. Burkholderia pseudomallei is intrinsically resistant to aminoglycosides but a gentamicin-susceptible strain was discovered in Sarawak, Malaysian Borneo in 2010. We report the first occurrence of infectiv...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177064/ https://www.ncbi.nlm.nih.gov/pubmed/31020134 http://dx.doi.org/10.1093/ehjcr/yty055 |
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author | Sia, Tonnii Podin, Yuwana Chuah, Teik-Beng Wong, Jin-Shyan |
author_facet | Sia, Tonnii Podin, Yuwana Chuah, Teik-Beng Wong, Jin-Shyan |
author_sort | Sia, Tonnii |
collection | PubMed |
description | INTRODUCTION: As a causal organism in infective endocarditis, Burkholderia pseudomallei is rare. Burkholderia pseudomallei is intrinsically resistant to aminoglycosides but a gentamicin-susceptible strain was discovered in Sarawak, Malaysian Borneo in 2010. We report the first occurrence of infective endocarditis due to the gentamicin-susceptible strain of B. pseudomallei. CASE PRESENTATION: A 29-year-old man presented with pneumonia and melioidosis septicaemia. His condition was complicated with infective endocarditis and septic emboli to the brain. Despite difficulties in reaching a diagnosis, the patient was successfully treated using intravenous gentamicin and ceftazidime and was discharged well. DISCUSSION: The role of gentamicin in the treatment of the gentamicin-susceptible strain of B. pseudomallei remains unclear. |
format | Online Article Text |
id | pubmed-6177064 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61770642019-04-24 Melioidosis: an unusual cause of infective endocarditis: a case report Sia, Tonnii Podin, Yuwana Chuah, Teik-Beng Wong, Jin-Shyan Eur Heart J Case Rep Case Reports INTRODUCTION: As a causal organism in infective endocarditis, Burkholderia pseudomallei is rare. Burkholderia pseudomallei is intrinsically resistant to aminoglycosides but a gentamicin-susceptible strain was discovered in Sarawak, Malaysian Borneo in 2010. We report the first occurrence of infective endocarditis due to the gentamicin-susceptible strain of B. pseudomallei. CASE PRESENTATION: A 29-year-old man presented with pneumonia and melioidosis septicaemia. His condition was complicated with infective endocarditis and septic emboli to the brain. Despite difficulties in reaching a diagnosis, the patient was successfully treated using intravenous gentamicin and ceftazidime and was discharged well. DISCUSSION: The role of gentamicin in the treatment of the gentamicin-susceptible strain of B. pseudomallei remains unclear. Oxford University Press 2018-05-02 /pmc/articles/PMC6177064/ /pubmed/31020134 http://dx.doi.org/10.1093/ehjcr/yty055 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society of Cardiology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Reports Sia, Tonnii Podin, Yuwana Chuah, Teik-Beng Wong, Jin-Shyan Melioidosis: an unusual cause of infective endocarditis: a case report |
title | Melioidosis: an unusual cause of infective endocarditis: a case report |
title_full | Melioidosis: an unusual cause of infective endocarditis: a case report |
title_fullStr | Melioidosis: an unusual cause of infective endocarditis: a case report |
title_full_unstemmed | Melioidosis: an unusual cause of infective endocarditis: a case report |
title_short | Melioidosis: an unusual cause of infective endocarditis: a case report |
title_sort | melioidosis: an unusual cause of infective endocarditis: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177064/ https://www.ncbi.nlm.nih.gov/pubmed/31020134 http://dx.doi.org/10.1093/ehjcr/yty055 |
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