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BlasterJS: A novel interactive JavaScript visualisation component for BLAST alignment results

BACKGROUND: The wide range of potential applications has made the Basic Local Alignment Search Tool (BLAST) a ubiquitous tool in the field of Molecular Biology. Within this context, it is increasingly appealing to embed BLAST services within larger Web applications. RESULTS: This work introduces Bla...

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Detalles Bibliográficos
Autores principales: Blanco-Míguez, Aitor, Fdez-Riverola, Florentino, Sánchez, Borja, Lourenço, Anália
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177166/
https://www.ncbi.nlm.nih.gov/pubmed/30300406
http://dx.doi.org/10.1371/journal.pone.0205286
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author Blanco-Míguez, Aitor
Fdez-Riverola, Florentino
Sánchez, Borja
Lourenço, Anália
author_facet Blanco-Míguez, Aitor
Fdez-Riverola, Florentino
Sánchez, Borja
Lourenço, Anália
author_sort Blanco-Míguez, Aitor
collection PubMed
description BACKGROUND: The wide range of potential applications has made the Basic Local Alignment Search Tool (BLAST) a ubiquitous tool in the field of Molecular Biology. Within this context, it is increasingly appealing to embed BLAST services within larger Web applications. RESULTS: This work introduces BlasterJS viewer, a new JavaScript library for the lightweight development of Web-based applications supporting the visualisation of BLAST outputs. BlasterJS detaches from similar data viewers by focusing on the visual and interactive display of sequence similarity results and being completely independent of BLAST services. BlasterJS is compatible with the text outputs generated by the BLAST family of programs, namely BLASTp, BLASTn, BLASTx, tBLASTn, and tBLASTx, and works in all major Web browsers. Furthermore, BlasterJS is available through the EBI’s BioJS registry 5, which extends its potential use to a wider scope of bioinformatics applications. CONCLUSIONS: BlasterJS is new Javascript library that enables easy and seamless integration of visual and interactive representations of BLAST outputs in Web-based applications supporting sequence similarity search. BlasterJS is free accessible at http://sing-group.org/blasterjs/.
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spelling pubmed-61771662018-10-19 BlasterJS: A novel interactive JavaScript visualisation component for BLAST alignment results Blanco-Míguez, Aitor Fdez-Riverola, Florentino Sánchez, Borja Lourenço, Anália PLoS One Research Article BACKGROUND: The wide range of potential applications has made the Basic Local Alignment Search Tool (BLAST) a ubiquitous tool in the field of Molecular Biology. Within this context, it is increasingly appealing to embed BLAST services within larger Web applications. RESULTS: This work introduces BlasterJS viewer, a new JavaScript library for the lightweight development of Web-based applications supporting the visualisation of BLAST outputs. BlasterJS detaches from similar data viewers by focusing on the visual and interactive display of sequence similarity results and being completely independent of BLAST services. BlasterJS is compatible with the text outputs generated by the BLAST family of programs, namely BLASTp, BLASTn, BLASTx, tBLASTn, and tBLASTx, and works in all major Web browsers. Furthermore, BlasterJS is available through the EBI’s BioJS registry 5, which extends its potential use to a wider scope of bioinformatics applications. CONCLUSIONS: BlasterJS is new Javascript library that enables easy and seamless integration of visual and interactive representations of BLAST outputs in Web-based applications supporting sequence similarity search. BlasterJS is free accessible at http://sing-group.org/blasterjs/. Public Library of Science 2018-10-09 /pmc/articles/PMC6177166/ /pubmed/30300406 http://dx.doi.org/10.1371/journal.pone.0205286 Text en © 2018 Blanco-Míguez et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Blanco-Míguez, Aitor
Fdez-Riverola, Florentino
Sánchez, Borja
Lourenço, Anália
BlasterJS: A novel interactive JavaScript visualisation component for BLAST alignment results
title BlasterJS: A novel interactive JavaScript visualisation component for BLAST alignment results
title_full BlasterJS: A novel interactive JavaScript visualisation component for BLAST alignment results
title_fullStr BlasterJS: A novel interactive JavaScript visualisation component for BLAST alignment results
title_full_unstemmed BlasterJS: A novel interactive JavaScript visualisation component for BLAST alignment results
title_short BlasterJS: A novel interactive JavaScript visualisation component for BLAST alignment results
title_sort blasterjs: a novel interactive javascript visualisation component for blast alignment results
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177166/
https://www.ncbi.nlm.nih.gov/pubmed/30300406
http://dx.doi.org/10.1371/journal.pone.0205286
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