Assessing the function of pneumococcal neuraminidases NanA, NanB and NanC in in vitro and in vivo lung infection models using monoclonal antibodies

Streptococcus pneumoniae isolates express up to three neuraminidases (sialidases), NanA, NanB and NanC, all of which cleave the terminal sialic acid of glycan-structures that decorate host cell surfaces. Most research has focused on the role of NanA with limited investigations evaluating the roles o...

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Detalles Bibliográficos
Autores principales: Janesch, Philipp, Rouha, Harald, Badarau, Adriana, Stulik, Lukas, Mirkina, Irina, Caccamo, Marisa, Havlicek, Katharina, Maierhofer, Barbara, Weber, Susanne, Groß, Karin, Steinhäuser, Jacqueline, Zerbs, Manuel, Varga, Cecilia, Dolezilkova, Ivana, Maier, Sabine, Zauner, Gerhild, Nielson, Nels, Power, Christine A., Nagy, Eszter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177239/
https://www.ncbi.nlm.nih.gov/pubmed/30289054
http://dx.doi.org/10.1080/21505594.2018.1520545

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