IgM cleavage by Streptococcus suis reduces IgM bound to the bacterial surface and is a novel complement evasion mechanism

Streptococcus suis (S. suis) causes meningitis, arthritis and endocarditis in piglets. The aim of this study was to characterize the IgM degrading enzyme of S. suis (Ide(Ssuis)) and to investigate the role of IgM cleavage in evasion of the classical complement pathway and pathogenesis. Targeted muta...

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Detalles Bibliográficos
Autores principales: Rungelrath, Viktoria, Weiße, Christine, Schütze, Nicole, Müller, Uwe, Meurer, Marita, Rohde, Manfred, Seele, Jana, Valentin-Weigand, Peter, Kirschfink, Michael, Beineke, Andreas, Schrödl, Wieland, Bergmann, René, Baums, Christoph Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177247/
https://www.ncbi.nlm.nih.gov/pubmed/30001174
http://dx.doi.org/10.1080/21505594.2018.1496778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177247/
https://www.ncbi.nlm.nih.gov/pubmed/30001174
http://dx.doi.org/10.1080/21505594.2018.1496778

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