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Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference

Morphogenesis involves interactions of asymmetric cell populations to form complex multicellular patterns and structures comprised of distinct cell types. However, current methods to model morphogenic events lack control over cell-type co-emergence and offer little capability to selectively perturb...

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Detalles Bibliográficos
Autores principales:	Libby, Ashley RG, Joy, David A, So, Po-Lin, Mandegar, Mohammad A, Muncie, Jonathon M, Mendoza-Camacho, Federico N, Weaver, Valerie M, Conklin, Bruce R, McDevitt, Todd C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177255/ https://www.ncbi.nlm.nih.gov/pubmed/30298816 http://dx.doi.org/10.7554/eLife.36045

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