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Development of a Molecular Adjuvant to Enhance Antigen-Specific CD8(+) T Cell Responses

Despite promising progress in malaria vaccine development, an efficacious subunit vaccine against P. falciparum remains to be licensed and deployed. This study aimed to improve on the immunogenicity of the leading liver-stage vaccine candidate (ChAd63-MVA ME-TRAP), known to confer protection by elic...

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Detalles Bibliográficos
Autores principales: Halbroth, Benedict R., Sebastian, Sarah, Poyntz, Hazel C., Bregu, Migena, Cottingham, Matthew G., Hill, Adrian V. S., Spencer, Alexandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177389/
https://www.ncbi.nlm.nih.gov/pubmed/30301933
http://dx.doi.org/10.1038/s41598-018-33375-1