Simultaneous evaluation of anti-EGFR-induced tumour and adverse skin effects in a microfluidic human 3D co-culture model

Antibody therapies targeting the epithelial growth factor receptor (EGFR) are being increasingly applied in cancer therapy. However, increased tumour containment correlates proportionally with the severity of well-known adverse events in skin. The prediction of the latter is not currently possible i...

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Detalles Bibliográficos
Autores principales: Hübner, Juliane, Raschke, Marian, Rütschle, Isabel, Gräßle, Sarah, Hasenberg, Tobias, Schirrmann, Kerstin, Lorenz, Alexandra, Schnurre, Susanne, Lauster, Roland, Maschmeyer, Ilka, Steger-Hartmann, Thomas, Marx, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177413/
https://www.ncbi.nlm.nih.gov/pubmed/30301942
http://dx.doi.org/10.1038/s41598-018-33462-3

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