Cryo-EM structure of the hibernating Thermus thermophilus 100S ribosome reveals a protein-mediated dimerization mechanism

In response to cellular stresses bacteria conserve energy by dimerization of ribosomes into inactive hibernating 100S ribosome particles. Ribosome dimerization in Thermus thermophilus is facilitated by hibernation-promoting factor (TtHPF). In this study we demonstrate high sensitivity of Tt100S form...

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Detalles Bibliográficos
Autores principales: Flygaard, Rasmus Kock, Boegholm, Niels, Yusupov, Marat, Jenner, Lasse B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177447/
https://www.ncbi.nlm.nih.gov/pubmed/30301898
http://dx.doi.org/10.1038/s41467-018-06724-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177447/
https://www.ncbi.nlm.nih.gov/pubmed/30301898
http://dx.doi.org/10.1038/s41467-018-06724-x

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