Nitazoxanide, an antiprotozoal drug, inhibits late-stage autophagy and promotes ING1-induced cell cycle arrest in glioblastoma

Glioblastoma is the most common and aggressive primary brain tumor in adults. New drug design and development is still a major challenge for glioma treatment. Increasing evidence has shown that nitazoxanide, an antiprotozoal drug, has a novel antitumor role in various tumors and exhibits multiple mo...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoxiong, Shen, Chen, Liu, Zhendong, Peng, Fei, Chen, Xin, Yang, Guang, Zhang, Daming, Yin, Zhiqin, Ma, Jichao, Zheng, Zhixing, Zhao, Boxian, Liu, Huailei, Wang, Ligang, Wu, Jianing, Han, Dayong, Wang, Kaikai, Zhong, Chen, Hou, Xu, Zhao, Wenyang, Shu, Mengting, Wang, Xinzhuang, Zhao, Shiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177448/
https://www.ncbi.nlm.nih.gov/pubmed/30302016
http://dx.doi.org/10.1038/s41419-018-1058-z

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