Cargando…
Molecular signalling towards mitochondrial breakdown is enhanced in skeletal muscle of patients with chronic obstructive pulmonary disease (COPD)
Loss of skeletal muscle mitochondrial oxidative capacity is well-established in patients with COPD, but the role of mitochondrial breakdown herein is largely unexplored. Currently, we studied if mitochondrial breakdown signalling is increased in skeletal muscle of COPD patients and associates with t...
Autores principales: | Leermakers, P. A., Schols, A. M. W. J., Kneppers, A. E. M., Kelders, M. C. J. M., de Theije, C. C., Lainscak, M., Gosker, H. R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177478/ https://www.ncbi.nlm.nih.gov/pubmed/30302028 http://dx.doi.org/10.1038/s41598-018-33471-2 |
Ejemplares similares
-
Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation
por: Leermakers, Pieter A., et al.
Publicado: (2019) -
Distinct skeletal muscle molecular responses to pulmonary rehabilitation in chronic obstructive pulmonary disease: a cluster analysis
por: Kneppers, Anita E.M., et al.
Publicado: (2019) -
Impaired Skeletal Muscle Kynurenine Metabolism in Patients with Chronic Obstructive Pulmonary Disease
por: Gosker, Harry R., et al.
Publicado: (2019) -
Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle
por: Leermakers, Pieter A., et al.
Publicado: (2020) -
Towards Personalized Management of Sarcopenia in COPD
por: van Bakel, Sophie I J, et al.
Publicado: (2021)