Knockdown of PKM2 suppresses tumor progression in human cervical cancer by modulating epithelial–mesenchymal transition via Wnt/β-catenin signaling

BACKGROUND: Pyruvate kinase isozyme type M2 (PKM2) is a key glycolytic enzyme and is upregulated in multiple human malignancies. However, the role of PKM2 in human cervical cancer (CC) remains elusive. Thus, this study explored the role of PKM2 in CC by detecting its expression patterns in human CC...

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Detalles Bibliográficos
Autores principales: Lin, Yanzhu, Meng, Fanqing, Lu, Zhiyuan, Chen, Kai, Tao, Yalan, Ouyang, Yi, Cao, Xinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177516/
https://www.ncbi.nlm.nih.gov/pubmed/30323675
http://dx.doi.org/10.2147/CMAR.S178219

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