Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement

Background. ‘Maturity-Onset Diabetes of the Young' (MODY) or monogenic diabetes accounts for approximately 1–2% of diabetes and is frequently misdiagnosed as type 1 or type 2 diabetes. Here we report a case of a 19-year-old pregnant woman with a MODY 3 diabetes expecting a child to a father wit...

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Detalles Bibliográficos
Autores principales: Mikuscheva, Anastasia, Mekhail, Adel, Wheeler, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178147/
https://www.ncbi.nlm.nih.gov/pubmed/30356406
http://dx.doi.org/10.1155/2018/9451061
Descripción
Sumario:Background. ‘Maturity-Onset Diabetes of the Young' (MODY) or monogenic diabetes accounts for approximately 1–2% of diabetes and is frequently misdiagnosed as type 1 or type 2 diabetes. Here we report a case of a 19-year-old pregnant woman with a MODY 3 diabetes expecting a child to a father with MODY 2 diabetes. Possible inheritance scenarios are described and the implications of these scenarios on the pregnancy and infant are discussed. In addition, the pregnancy was complicated by drastically falling insulin requirements in the mother in the 3(rd) trimester as well as preterm labour and delivery at 33+4 weeks of gestation.

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