Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement

Background. ‘Maturity-Onset Diabetes of the Young' (MODY) or monogenic diabetes accounts for approximately 1–2% of diabetes and is frequently misdiagnosed as type 1 or type 2 diabetes. Here we report a case of a 19-year-old pregnant woman with a MODY 3 diabetes expecting a child to a father wit...

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Autores principales: Mikuscheva, Anastasia, Mekhail, Adel, Wheeler, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178147/
https://www.ncbi.nlm.nih.gov/pubmed/30356406
http://dx.doi.org/10.1155/2018/9451061
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author Mikuscheva, Anastasia
Mekhail, Adel
Wheeler, Benjamin J.
author_facet Mikuscheva, Anastasia
Mekhail, Adel
Wheeler, Benjamin J.
author_sort Mikuscheva, Anastasia
collection PubMed
description Background. ‘Maturity-Onset Diabetes of the Young' (MODY) or monogenic diabetes accounts for approximately 1–2% of diabetes and is frequently misdiagnosed as type 1 or type 2 diabetes. Here we report a case of a 19-year-old pregnant woman with a MODY 3 diabetes expecting a child to a father with MODY 2 diabetes. Possible inheritance scenarios are described and the implications of these scenarios on the pregnancy and infant are discussed. In addition, the pregnancy was complicated by drastically falling insulin requirements in the mother in the 3(rd) trimester as well as preterm labour and delivery at 33+4 weeks of gestation.
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spelling pubmed-61781472018-10-23 Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement Mikuscheva, Anastasia Mekhail, Adel Wheeler, Benjamin J. Case Rep Obstet Gynecol Case Report Background. ‘Maturity-Onset Diabetes of the Young' (MODY) or monogenic diabetes accounts for approximately 1–2% of diabetes and is frequently misdiagnosed as type 1 or type 2 diabetes. Here we report a case of a 19-year-old pregnant woman with a MODY 3 diabetes expecting a child to a father with MODY 2 diabetes. Possible inheritance scenarios are described and the implications of these scenarios on the pregnancy and infant are discussed. In addition, the pregnancy was complicated by drastically falling insulin requirements in the mother in the 3(rd) trimester as well as preterm labour and delivery at 33+4 weeks of gestation. Hindawi 2018-09-26 /pmc/articles/PMC6178147/ /pubmed/30356406 http://dx.doi.org/10.1155/2018/9451061 Text en Copyright © 2018 Anastasia Mikuscheva et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mikuscheva, Anastasia
Mekhail, Adel
Wheeler, Benjamin J.
Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement
title Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement
title_full Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement
title_fullStr Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement
title_full_unstemmed Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement
title_short Pregnancy Complicated by Maternal MODY 3 and Paternal MODY 2 Diabetes and Subsequent Rapidly Falling Insulin Requirement
title_sort pregnancy complicated by maternal mody 3 and paternal mody 2 diabetes and subsequent rapidly falling insulin requirement
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178147/
https://www.ncbi.nlm.nih.gov/pubmed/30356406
http://dx.doi.org/10.1155/2018/9451061
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AT wheelerbenjaminj pregnancycomplicatedbymaternalmody3andpaternalmody2diabetesandsubsequentrapidlyfallinginsulinrequirement

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