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Tracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension

Blood pressure (BP) tracking from childhood to adulthood has two aspects: the ranking stability relative to others over time and the prediction of future values. This study investigates BP tracking in children and adolescents in Germany in the context of hypertension risk factors. BP was measured an...

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Autores principales: Sarganas, Giselle, Schaffrath Rosario, Angelika, Niessner, Claudia, Woll, Alexander, Neuhauser, Hannelore K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178151/
https://www.ncbi.nlm.nih.gov/pubmed/30356390
http://dx.doi.org/10.1155/2018/8429891
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author Sarganas, Giselle
Schaffrath Rosario, Angelika
Niessner, Claudia
Woll, Alexander
Neuhauser, Hannelore K.
author_facet Sarganas, Giselle
Schaffrath Rosario, Angelika
Niessner, Claudia
Woll, Alexander
Neuhauser, Hannelore K.
author_sort Sarganas, Giselle
collection PubMed
description Blood pressure (BP) tracking from childhood to adulthood has two aspects: the ranking stability relative to others over time and the prediction of future values. This study investigates BP tracking in children and adolescents in Germany in the context of hypertension risk factors. BP was measured and analyzed in 2542 participants of the German Health Examination Survey for Children and Adolescents (t(0) 2003-2006; 3 to 17-year olds) and of a six year follow-up “Motorik Modul” (t(1) 2009-2012; 9 to 24-year olds). BP tracking coefficients were calculated from Spearman's rank-order correlations. Predictive values and logistic regression models were used to forecast t(1)-BP above the hypertension threshold from t(0)-BP as well as from baseline and follow-up hypertension risk factors. BP tracking was moderate (0.33-0.50 for SBP and 0.19-0.39 for DBP) with no statistically significant differences between sex and age groups. Baseline hypertensive BP was the strongest independent predictor of hypertensive BP at follow-up (OR 4.3 and 3.4 for age groups 3-10 and 11-17 years) after adjusting for sex, BMI trajectories, birthweight, parental hypertension, and age-group dependent-sports/physical activity. However, the positive predictive value of baseline hypertensive BP for hypertensive BP at follow-up in 3- to 10-year olds was only 39% (34% in 11- to 17-year olds) and increased only moderately in the presence of additional risk factors. Our analysis with population-based data from Germany shows that BP in children and adolescents tracks only moderately over six years. BP in childhood is the strongest independent predictor of future BP but its predictive value is limited.
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spelling pubmed-61781512018-10-23 Tracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension Sarganas, Giselle Schaffrath Rosario, Angelika Niessner, Claudia Woll, Alexander Neuhauser, Hannelore K. Int J Hypertens Research Article Blood pressure (BP) tracking from childhood to adulthood has two aspects: the ranking stability relative to others over time and the prediction of future values. This study investigates BP tracking in children and adolescents in Germany in the context of hypertension risk factors. BP was measured and analyzed in 2542 participants of the German Health Examination Survey for Children and Adolescents (t(0) 2003-2006; 3 to 17-year olds) and of a six year follow-up “Motorik Modul” (t(1) 2009-2012; 9 to 24-year olds). BP tracking coefficients were calculated from Spearman's rank-order correlations. Predictive values and logistic regression models were used to forecast t(1)-BP above the hypertension threshold from t(0)-BP as well as from baseline and follow-up hypertension risk factors. BP tracking was moderate (0.33-0.50 for SBP and 0.19-0.39 for DBP) with no statistically significant differences between sex and age groups. Baseline hypertensive BP was the strongest independent predictor of hypertensive BP at follow-up (OR 4.3 and 3.4 for age groups 3-10 and 11-17 years) after adjusting for sex, BMI trajectories, birthweight, parental hypertension, and age-group dependent-sports/physical activity. However, the positive predictive value of baseline hypertensive BP for hypertensive BP at follow-up in 3- to 10-year olds was only 39% (34% in 11- to 17-year olds) and increased only moderately in the presence of additional risk factors. Our analysis with population-based data from Germany shows that BP in children and adolescents tracks only moderately over six years. BP in childhood is the strongest independent predictor of future BP but its predictive value is limited. Hindawi 2018-09-26 /pmc/articles/PMC6178151/ /pubmed/30356390 http://dx.doi.org/10.1155/2018/8429891 Text en Copyright © 2018 Giselle Sarganas et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sarganas, Giselle
Schaffrath Rosario, Angelika
Niessner, Claudia
Woll, Alexander
Neuhauser, Hannelore K.
Tracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension
title Tracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension
title_full Tracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension
title_fullStr Tracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension
title_full_unstemmed Tracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension
title_short Tracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension
title_sort tracking of blood pressure in children and adolescents in germany in the context of risk factors for hypertension
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178151/
https://www.ncbi.nlm.nih.gov/pubmed/30356390
http://dx.doi.org/10.1155/2018/8429891
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