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Activation of CD137 Signaling Enhances Vascular Calcification through c-Jun N-Terminal Kinase-Dependent Disruption of Autophagic Flux

BACKGROUND: Vascular calcification is widespread and clinically significant, contributing to substantial morbidity and mortality. Calcifying vascular cells are partly derived from local vascular smooth muscle cells (VSMCs), which can undergo chondrogenic or osteogenic differentiation under inflammat...

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Detalles Bibliográficos
Autores principales:	Chen, Rui, Xu, Yao, Zhong, Wei, Li, Bo, Yang, Ping, Wang, Zhong Qun, Shao, Chen, Wang, Cui Ping, Yan, Jin Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178178/ https://www.ncbi.nlm.nih.gov/pubmed/30356425 http://dx.doi.org/10.1155/2018/8407137

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