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Synthesis of dihydroquinazolines from 2-aminobenzylamine: N(3)-aryl derivatives with electron-withdrawing groups

The sequential N-functionalization of 2-aminobenzylamine (2-ABA) followed by cyclodehydration allowed for a straightforward and efficient synthesis of 3,4-dihydroquinazolines with N-aryl substituents bearing electron-withdrawing groups. The sequence involves an initial S(N)Ar displacement, N-acylati...

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Detalles Bibliográficos
Autores principales:	Gruber, Nadia, Díaz, Jimena E, Orelli, Liliana R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2018
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178284/ https://www.ncbi.nlm.nih.gov/pubmed/30344774 http://dx.doi.org/10.3762/bjoc.14.227

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