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Impact of your results: Beyond the relative risk

Universally, reporting guidelines emphasize the importance of using point estimates that indicate the strength of an effect. A single statement of the presence (or absence) of “statistical significance” and/or a P value alone do not provide sufficient information. Instead, an estimate of relative ri...

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Detalles Bibliográficos
Autores principales: Siegerink, Bob, Rohmann, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178613/
https://www.ncbi.nlm.nih.gov/pubmed/30349882
http://dx.doi.org/10.1002/rth2.12148
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author Siegerink, Bob
Rohmann, Jessica L.
author_facet Siegerink, Bob
Rohmann, Jessica L.
author_sort Siegerink, Bob
collection PubMed
description Universally, reporting guidelines emphasize the importance of using point estimates that indicate the strength of an effect. A single statement of the presence (or absence) of “statistical significance” and/or a P value alone do not provide sufficient information. Instead, an estimate of relative risk with a corresponding confidence interval should be routinely provided. Unfortunately, the context of the reported relative risk is often omitted, thereby hampering the readers’ understanding of the impact of the results. Additionally, commonly used binary outcomes might not be sensitive enough to fully convey the clinical relevance of an intervention or risk factor. This tutorial underlines the role of the context of results presented in clinical research papers. It also provides suggestions of meaningful ways to illustrate the impact of your own results by going beyond the relative risk.
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spelling pubmed-61786132018-10-22 Impact of your results: Beyond the relative risk Siegerink, Bob Rohmann, Jessica L. Res Pract Thromb Haemost Tutorials Universally, reporting guidelines emphasize the importance of using point estimates that indicate the strength of an effect. A single statement of the presence (or absence) of “statistical significance” and/or a P value alone do not provide sufficient information. Instead, an estimate of relative risk with a corresponding confidence interval should be routinely provided. Unfortunately, the context of the reported relative risk is often omitted, thereby hampering the readers’ understanding of the impact of the results. Additionally, commonly used binary outcomes might not be sensitive enough to fully convey the clinical relevance of an intervention or risk factor. This tutorial underlines the role of the context of results presented in clinical research papers. It also provides suggestions of meaningful ways to illustrate the impact of your own results by going beyond the relative risk. John Wiley and Sons Inc. 2018-09-30 /pmc/articles/PMC6178613/ /pubmed/30349882 http://dx.doi.org/10.1002/rth2.12148 Text en © 2018 The Authors. Research and Practice in Thrombosis and Haemostasis published by Wiley Periodicals, Inc on behalf of International Society on Thrombosis and Haemostasis. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Tutorials
Siegerink, Bob
Rohmann, Jessica L.
Impact of your results: Beyond the relative risk
title Impact of your results: Beyond the relative risk
title_full Impact of your results: Beyond the relative risk
title_fullStr Impact of your results: Beyond the relative risk
title_full_unstemmed Impact of your results: Beyond the relative risk
title_short Impact of your results: Beyond the relative risk
title_sort impact of your results: beyond the relative risk
topic Tutorials
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178613/
https://www.ncbi.nlm.nih.gov/pubmed/30349882
http://dx.doi.org/10.1002/rth2.12148
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