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Potential application value of xenon in stroke treatment

Stroke is an acute disease with extremely high mortality and disability, including ischemic stroke and hemorrhagic stroke. Currently only limited drugs and treatments have been shown to have neuroprotective effects in stroke. As a medical gas, xenon has been proven to have neuroprotective effect in...

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Autores principales: Zhao, Chong-Shun, Li, Hao, Wang, Zhong, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178644/
https://www.ncbi.nlm.nih.gov/pubmed/30319767
http://dx.doi.org/10.4103/2045-9912.241077
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author Zhao, Chong-Shun
Li, Hao
Wang, Zhong
Chen, Gang
author_facet Zhao, Chong-Shun
Li, Hao
Wang, Zhong
Chen, Gang
author_sort Zhao, Chong-Shun
collection PubMed
description Stroke is an acute disease with extremely high mortality and disability, including ischemic stroke and hemorrhagic stroke. Currently only limited drugs and treatments have been shown to have neuroprotective effects in stroke. As a medical gas, xenon has been proven to have neuroprotective effect in considerable amount of previous study. Its unique properties are different from other neuroprotective agents, making it is promising to play a special therapeutic role in stroke, either alone or in combination with other treatments. In this article, we aim to review the role of xenon in the treatment of stroke, and summarize the mechanism of using xenon to produce therapeutic effects after stroke according to the existing research. Moreover, we intend to explore and demonstrate the feasibility and safety of xenon for clinical treatment of stroke. Despite the disadvantages of difficulty in obtaining and being expensive, as long as the use of reasonable methods, xenon can play an important role in the treatment of stroke.
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spelling pubmed-61786442018-10-12 Potential application value of xenon in stroke treatment Zhao, Chong-Shun Li, Hao Wang, Zhong Chen, Gang Med Gas Res Review Stroke is an acute disease with extremely high mortality and disability, including ischemic stroke and hemorrhagic stroke. Currently only limited drugs and treatments have been shown to have neuroprotective effects in stroke. As a medical gas, xenon has been proven to have neuroprotective effect in considerable amount of previous study. Its unique properties are different from other neuroprotective agents, making it is promising to play a special therapeutic role in stroke, either alone or in combination with other treatments. In this article, we aim to review the role of xenon in the treatment of stroke, and summarize the mechanism of using xenon to produce therapeutic effects after stroke according to the existing research. Moreover, we intend to explore and demonstrate the feasibility and safety of xenon for clinical treatment of stroke. Despite the disadvantages of difficulty in obtaining and being expensive, as long as the use of reasonable methods, xenon can play an important role in the treatment of stroke. Medknow Publications & Media Pvt Ltd 2018-09-25 /pmc/articles/PMC6178644/ /pubmed/30319767 http://dx.doi.org/10.4103/2045-9912.241077 Text en Copyright: © 2018 Medical Gas Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review
Zhao, Chong-Shun
Li, Hao
Wang, Zhong
Chen, Gang
Potential application value of xenon in stroke treatment
title Potential application value of xenon in stroke treatment
title_full Potential application value of xenon in stroke treatment
title_fullStr Potential application value of xenon in stroke treatment
title_full_unstemmed Potential application value of xenon in stroke treatment
title_short Potential application value of xenon in stroke treatment
title_sort potential application value of xenon in stroke treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178644/
https://www.ncbi.nlm.nih.gov/pubmed/30319767
http://dx.doi.org/10.4103/2045-9912.241077
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