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Potential application value of xenon in stroke treatment
Stroke is an acute disease with extremely high mortality and disability, including ischemic stroke and hemorrhagic stroke. Currently only limited drugs and treatments have been shown to have neuroprotective effects in stroke. As a medical gas, xenon has been proven to have neuroprotective effect in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178644/ https://www.ncbi.nlm.nih.gov/pubmed/30319767 http://dx.doi.org/10.4103/2045-9912.241077 |
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author | Zhao, Chong-Shun Li, Hao Wang, Zhong Chen, Gang |
author_facet | Zhao, Chong-Shun Li, Hao Wang, Zhong Chen, Gang |
author_sort | Zhao, Chong-Shun |
collection | PubMed |
description | Stroke is an acute disease with extremely high mortality and disability, including ischemic stroke and hemorrhagic stroke. Currently only limited drugs and treatments have been shown to have neuroprotective effects in stroke. As a medical gas, xenon has been proven to have neuroprotective effect in considerable amount of previous study. Its unique properties are different from other neuroprotective agents, making it is promising to play a special therapeutic role in stroke, either alone or in combination with other treatments. In this article, we aim to review the role of xenon in the treatment of stroke, and summarize the mechanism of using xenon to produce therapeutic effects after stroke according to the existing research. Moreover, we intend to explore and demonstrate the feasibility and safety of xenon for clinical treatment of stroke. Despite the disadvantages of difficulty in obtaining and being expensive, as long as the use of reasonable methods, xenon can play an important role in the treatment of stroke. |
format | Online Article Text |
id | pubmed-6178644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-61786442018-10-12 Potential application value of xenon in stroke treatment Zhao, Chong-Shun Li, Hao Wang, Zhong Chen, Gang Med Gas Res Review Stroke is an acute disease with extremely high mortality and disability, including ischemic stroke and hemorrhagic stroke. Currently only limited drugs and treatments have been shown to have neuroprotective effects in stroke. As a medical gas, xenon has been proven to have neuroprotective effect in considerable amount of previous study. Its unique properties are different from other neuroprotective agents, making it is promising to play a special therapeutic role in stroke, either alone or in combination with other treatments. In this article, we aim to review the role of xenon in the treatment of stroke, and summarize the mechanism of using xenon to produce therapeutic effects after stroke according to the existing research. Moreover, we intend to explore and demonstrate the feasibility and safety of xenon for clinical treatment of stroke. Despite the disadvantages of difficulty in obtaining and being expensive, as long as the use of reasonable methods, xenon can play an important role in the treatment of stroke. Medknow Publications & Media Pvt Ltd 2018-09-25 /pmc/articles/PMC6178644/ /pubmed/30319767 http://dx.doi.org/10.4103/2045-9912.241077 Text en Copyright: © 2018 Medical Gas Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Zhao, Chong-Shun Li, Hao Wang, Zhong Chen, Gang Potential application value of xenon in stroke treatment |
title | Potential application value of xenon in stroke treatment |
title_full | Potential application value of xenon in stroke treatment |
title_fullStr | Potential application value of xenon in stroke treatment |
title_full_unstemmed | Potential application value of xenon in stroke treatment |
title_short | Potential application value of xenon in stroke treatment |
title_sort | potential application value of xenon in stroke treatment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178644/ https://www.ncbi.nlm.nih.gov/pubmed/30319767 http://dx.doi.org/10.4103/2045-9912.241077 |
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