Cargando…

Fast Generation of Functional Subtype Astrocytes from Human Pluripotent Stem Cells

Differentiation of astrocytes from human pluripotent stem cells (hPSCs) is a tedious and variable process. This hampers the study of hPSC-generated astrocytes in disease processes and drug development. By using CRISPR/Cas9-mediated inducible expression of NFIA or NFIA plus SOX9 in hPSCs, we develope...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiang, Tao, Yezheng, Bradley, Robert, Du, Zhongwei, Tao, Yunlong, Kong, Linghai, Dong, Yi, Jones, Jeffrey, Yan, Yuanwei, Harder, Cole R.K., Friedman, Lindsay Morgan, Bilal, Magd, Hoffmann, Brianna, Zhang, Su-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178885/ https://www.ncbi.nlm.nih.gov/pubmed/30269954 http://dx.doi.org/10.1016/j.stemcr.2018.08.019

Ejemplares similares

Fear Conditioning Downregulates Rac1 Activity in the Basolateral Amygdala Astrocytes to Facilitate the Formation of Fear Memory
por: Liao, Zhaohui, et al.
Publicado: (2017)

Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes
por: Jones, Jeffrey R., et al.
Publicado: (2018)

Cortical Astrocyte Progenitors and Astrocytes from Human Pluripotent Stem Cells
por: Battistella, Ingrid, et al.
Publicado: (2023)

Olig2-Lineage Astrocytes: A Distinct Subtype of Astrocytes That Differs from GFAP Astrocytes
por: Tatsumi, Kouko, et al.
Publicado: (2018)

Diverse subtypes of astrocytes and their development during corticogenesis
por: Tabata, Hidenori
Publicado: (2015)

Regionally diverse astrocyte subtypes and their heterogeneous response to EAE
por: Borggrewe, Malte, et al.
Publicado: (2020)

A Defined and Scalable Peptide-Based Platform for the Generation of Human Pluripotent Stem Cell-Derived Astrocytes
por: Raman, Sreedevi, et al.
Publicado: (2020)

Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes
por: Suga, Mika, et al.
Publicado: (2019)

Human Astrocytes Model Derived from Induced Pluripotent Stem Cells
por: Leventoux, Nicolas, et al.
Publicado: (2020)

Metabolic Assessment of Human Induced Pluripotent Stem Cells-Derived Astrocytes and Fetal Primary Astrocytes: Lactate and Glucose Turnover
por: Matthiesen, Isabelle, et al.
Publicado: (2022)

Identification of region-specific astrocyte subtypes at single cell resolution
por: Batiuk, Mykhailo Y., et al.
Publicado: (2020)

High-Efficient Generation of Induced Pluripotent Stem Cells from Human Astrocytes
por: Ruiz, Sergio, et al.
Publicado: (2010)

An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells
por: TCW, Julia, et al.
Publicado: (2017)

Generation of the Human Pluripotent Stem-Cell-Derived Astrocyte Model with Forebrain Identity
por: Peteri, Ulla-Kaisa, et al.
Publicado: (2021)

Insights into Human-Induced Pluripotent Stem Cell-Derived Astrocytes in Neurodegenerative Disorders
por: Kumar, Mandeep, et al.
Publicado: (2022)

Establishment of autaptic culture with human-induced pluripotent stem cell-derived astrocytes
por: Uchino, Kouya, et al.
Publicado: (2022)

Astrocyte Subtype Vulnerability in Stem Cell Models of Vanishing White Matter
por: Leferink, Prisca S., et al.
Publicado: (2019)

Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells
por: Santos, Renata, et al.
Publicado: (2017)

Multivariate analysis reveals differentially expressed genes among distinct subtypes of diffuse astrocytic gliomas: diagnostic implications
por: González-García, Nerea, et al.
Publicado: (2020)

Small is fast: astrocytic glucose and lactate metabolism at cellular resolution
por: Barros, L. F., et al.
Publicado: (2013)

Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder Research
por: Chandrasekaran, Abinaya, et al.
Publicado: (2016)

Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms
por: Oksanen, Minna, et al.
Publicado: (2019)

Protocol to differentiate monolayer human induced pluripotent stem cells into inflammatory responsive astrocytes
por: Giordano, Anna Maria Sole, et al.
Publicado: (2023)

Inducing Different Neuronal Subtypes from Astrocytes in the Injured Mouse Cerebral Cortex
por: Mattugini, Nicola, et al.
Publicado: (2019)

Gene Enrichment Analysis of Astrocyte Subtypes in Psychiatric Disorders and Psychotropic Medication Datasets
por: Zhang, Xiaolu, et al.
Publicado: (2022)

Studying Heterotypic Cell–Cell Interactions in the Human Brain Using Pluripotent Stem Cell Models for Neurodegeneration
por: Song, Liqing, et al.
Publicado: (2019)

The Use of Pluripotent Stem Cell-Derived Organoids to Study Extracellular Matrix Development during Neural Degeneration
por: Yan, Yuanwei, et al.
Publicado: (2019)

401 Eliminating System xc- Signaling Between Astrocytes and Neurons Selectively Impairs Complex Cognition
por: Simand, Gregory, et al.
Publicado: (2022)

511 Eliminating System xc- Signaling Between Astrocytes and Neurons Selectively Impairs Complex Cognition
por: Simandl, Gregory, et al.
Publicado: (2023)

Neuroinflammatory astrocytes generated from cord blood-derived human induced pluripotent stem cells
por: Zhou, Qiong, et al.
Publicado: (2019)

Modeling Neurodevelopmental and Neuropsychiatric Diseases with Astrocytes Derived from Human-Induced Pluripotent Stem Cells
por: Ren, Baiyan, et al.
Publicado: (2021)

Differentiation of functional astrocytes from human-induced pluripotent stem cells in chemically defined media
por: Perriot, Sylvain, et al.
Publicado: (2021)

A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells
por: Jovanovic, Vukasin M., et al.
Publicado: (2023)

Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells
por: Berryer, Martin H., et al.
Publicado: (2023)

Regulation of astrocyte proliferation by prostaglandin E(2) and the α subtype of protein kinase C
por: Sawada, Makoto, et al.
Publicado: (1993)

Transcriptome profiling of the Olig2-expressing astrocyte subtype reveals their unique molecular signature
por: Ohayon, David, et al.
Publicado: (2021)

Comparison of the Gene Expression Profiles of Human Fetal Cortical Astrocytes with Pluripotent Stem Cell Derived Neural Stem Cells Identifies Human Astrocyte Markers and Signaling Pathways and Transcription Factors Active in Human Astrocytes
por: Malik, Nasir, et al.
Publicado: (2014)

Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells
por: Nickolls, Alec R., et al.
Publicado: (2020)

Isolation of human pluripotent stem cell-derived sensory neuron subtypes by immunopanning
por: Saito-Diaz, Kenyi, et al.
Publicado: (2023)

A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies
por: Krencik, Robert, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_krv2soeu551tajprutkll8d1ji