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Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen
Background: Little is known about the impact of nutrients on cellular transcriptional responses, especially in face of environmental stressors such as oxygen deprivation. Hypoxia-inducible factors (HIF) coordinate the expression of genes essential for adaptation to oxygen-deprived environments. A se...
Autores principales: | Lai, Alvina G., Forde, Donall, Chang, Wai Hoong, Yuan, Fang, Zhuang, Xiaodong, Orbegozo Rubio, Claudia, Song, Chun-Xiao, McKeating, Jane A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178907/ https://www.ncbi.nlm.nih.gov/pubmed/30345392 http://dx.doi.org/10.12688/wellcomeopenres.14839.1 |
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