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Transcription-associated histone pruning demarcates macroH2A chromatin domains

The histone variant macroH2A occupies large repressive domains throughout the genome, however mechanisms underlying its precise deposition remain poorly understood. Here, we characterized de novo chromatin deposition of macroH2A2 using temporal genomic profiling in murine-derived fibroblasts devoid...

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Detalles Bibliográficos
Autores principales:	Sun, Zhen, Filipescu, Dan, Andrade, Joshua, Gaspar-Maia, Alexandre, Ueberheide, Beatrix, Bernstein, Emily
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178985/ https://www.ncbi.nlm.nih.gov/pubmed/30291361 http://dx.doi.org/10.1038/s41594-018-0134-5

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