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Surgical therapy of cutaneous squamous cell carcinoma: our experience

Introduction: Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, with an excellent prognosis after surgical removal. However, nodal metastasis are present in about 5% of cases and the death rate is about 2%. Presentation of case: The aim of this study is to report our ex...

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Autores principales: Simonacci, Francesco, Bertozzi, Nicolò, Grieco, Michele Pio, Grignaffini, Eugenio, Raposio, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179017/
https://www.ncbi.nlm.nih.gov/pubmed/29957758
http://dx.doi.org/10.23750/abm.v89i2.6189
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author Simonacci, Francesco
Bertozzi, Nicolò
Grieco, Michele Pio
Grignaffini, Eugenio
Raposio, Edoardo
author_facet Simonacci, Francesco
Bertozzi, Nicolò
Grieco, Michele Pio
Grignaffini, Eugenio
Raposio, Edoardo
author_sort Simonacci, Francesco
collection PubMed
description Introduction: Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, with an excellent prognosis after surgical removal. However, nodal metastasis are present in about 5% of cases and the death rate is about 2%. Presentation of case: The aim of this study is to report our experience about the surgical treatment of cSCC at the Cutaneous, Regenerative, Mininvasive and Plastic Surgery Unit, University of Parma, Italy, between January 2014 and February 2016. We statistically analyzed the group of patients regarding the average age, gender, localization and size of the lesions. The surgical margins of the excisions are studied and we report the results obtained after a follow up of 3 to 25 months. Discussion: Between January 2014 and February 2016 in our Cutaneous, Regenerative, Mininvasive and Plastic Surgery Unit, we removed 36 squamous cell carcinomas, including 11 cSCCs in situ. The average annual incidence of squamous cell carcinoma in northeast of Italy is about 28,9 cases per 100,000 individuals.The number of cSCCs that we removed is lower than the Italian average. In our opinion, this is due to an increase in the early diagnosis of precancerous lesions and their medical or surgical treatment. This reduces the incidence of squamous cell carcinomas developing from precancerous lesions. Conclusion: The excision of cutaneous squamous cell carcinoma should be undertaken with a safety margin of at least 0.9 mm to minimize recurrence and metastasis. (www.actabiomedica.it)
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spelling pubmed-61790172019-05-08 Surgical therapy of cutaneous squamous cell carcinoma: our experience Simonacci, Francesco Bertozzi, Nicolò Grieco, Michele Pio Grignaffini, Eugenio Raposio, Edoardo Acta Biomed Original Article Introduction: Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, with an excellent prognosis after surgical removal. However, nodal metastasis are present in about 5% of cases and the death rate is about 2%. Presentation of case: The aim of this study is to report our experience about the surgical treatment of cSCC at the Cutaneous, Regenerative, Mininvasive and Plastic Surgery Unit, University of Parma, Italy, between January 2014 and February 2016. We statistically analyzed the group of patients regarding the average age, gender, localization and size of the lesions. The surgical margins of the excisions are studied and we report the results obtained after a follow up of 3 to 25 months. Discussion: Between January 2014 and February 2016 in our Cutaneous, Regenerative, Mininvasive and Plastic Surgery Unit, we removed 36 squamous cell carcinomas, including 11 cSCCs in situ. The average annual incidence of squamous cell carcinoma in northeast of Italy is about 28,9 cases per 100,000 individuals.The number of cSCCs that we removed is lower than the Italian average. In our opinion, this is due to an increase in the early diagnosis of precancerous lesions and their medical or surgical treatment. This reduces the incidence of squamous cell carcinomas developing from precancerous lesions. Conclusion: The excision of cutaneous squamous cell carcinoma should be undertaken with a safety margin of at least 0.9 mm to minimize recurrence and metastasis. (www.actabiomedica.it) Mattioli 1885 2018 /pmc/articles/PMC6179017/ /pubmed/29957758 http://dx.doi.org/10.23750/abm.v89i2.6189 Text en Copyright: © 2018 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Original Article
Simonacci, Francesco
Bertozzi, Nicolò
Grieco, Michele Pio
Grignaffini, Eugenio
Raposio, Edoardo
Surgical therapy of cutaneous squamous cell carcinoma: our experience
title Surgical therapy of cutaneous squamous cell carcinoma: our experience
title_full Surgical therapy of cutaneous squamous cell carcinoma: our experience
title_fullStr Surgical therapy of cutaneous squamous cell carcinoma: our experience
title_full_unstemmed Surgical therapy of cutaneous squamous cell carcinoma: our experience
title_short Surgical therapy of cutaneous squamous cell carcinoma: our experience
title_sort surgical therapy of cutaneous squamous cell carcinoma: our experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179017/
https://www.ncbi.nlm.nih.gov/pubmed/29957758
http://dx.doi.org/10.23750/abm.v89i2.6189
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