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Baseline dasabuvir resistance in Hepatitis C virus from the genotypes 1, 2 and 3 and modeling of the NS5B-dasabuvir complex by the in silico approach

Background: Current combination treatments with direct-acting antiviral agents (DAAs) can cure more than 95% of hepatitis C virus (HCV) infections. However, resistance-associated substitutions (RASs) may emerge and can also be present in treatment-naïve patients. Methods, results and discussion: In...

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Detalles Bibliográficos
Autores principales:	Akaberi, Dario, Bergfors, Assar, Kjellin, Midori, Kameli, Nader, Lidemalm, Louise, Kolli, Bhavya, Shafer, Robert W., Palanisamy, Navaneethan, Lennerstrand, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179053/ https://www.ncbi.nlm.nih.gov/pubmed/30319736 http://dx.doi.org/10.1080/20008686.2018.1528117

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