An uncommon case of chronic myeloid leukemia with variant cytogenetics

Chronic Myeloid Leukemia (CML) is myeloproliferative neoplasm characterized by Philadelphia chromosome which is a balanced translocation between chromosome 9 and 22 in 90% of cases. However, variant cytogenetic still happens in 5-10% of cases, the importance of which is controversial as well as its...

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Autores principales: Abdulla, Mohammad A., Amer, Aliaa, Nawaz, Zafar, Abdullah, Ali S., Al-Sabbagh, Ahmad, Kohla, Samah, Nashwan, Abdulqadir J, Yassin, Mohamed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179100/
https://www.ncbi.nlm.nih.gov/pubmed/29633730
http://dx.doi.org/10.23750/abm.v89i3-S.7217
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author Abdulla, Mohammad A.
Amer, Aliaa
Nawaz, Zafar
Abdullah, Ali S.
Al-Sabbagh, Ahmad
Kohla, Samah
Nashwan, Abdulqadir J
Yassin, Mohamed A
author_facet Abdulla, Mohammad A.
Amer, Aliaa
Nawaz, Zafar
Abdullah, Ali S.
Al-Sabbagh, Ahmad
Kohla, Samah
Nashwan, Abdulqadir J
Yassin, Mohamed A
author_sort Abdulla, Mohammad A.
collection PubMed
description Chronic Myeloid Leukemia (CML) is myeloproliferative neoplasm characterized by Philadelphia chromosome which is a balanced translocation between chromosome 9 and 22 in 90% of cases. However, variant cytogenetic still happens in 5-10% of cases, the importance of which is controversial as well as its response to therapy, prognosis and progression to acute leukemias. Here we report a male patient with CML and variant cytogenetic who responded to low dose of Dasatinib (50 mg daily). (www.actabiomedica.it)
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spelling pubmed-61791002019-05-08 An uncommon case of chronic myeloid leukemia with variant cytogenetics Abdulla, Mohammad A. Amer, Aliaa Nawaz, Zafar Abdullah, Ali S. Al-Sabbagh, Ahmad Kohla, Samah Nashwan, Abdulqadir J Yassin, Mohamed A Acta Biomed Case Report Chronic Myeloid Leukemia (CML) is myeloproliferative neoplasm characterized by Philadelphia chromosome which is a balanced translocation between chromosome 9 and 22 in 90% of cases. However, variant cytogenetic still happens in 5-10% of cases, the importance of which is controversial as well as its response to therapy, prognosis and progression to acute leukemias. Here we report a male patient with CML and variant cytogenetic who responded to low dose of Dasatinib (50 mg daily). (www.actabiomedica.it) Mattioli 1885 2018 /pmc/articles/PMC6179100/ /pubmed/29633730 http://dx.doi.org/10.23750/abm.v89i3-S.7217 Text en Copyright: © 2018 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Case Report
Abdulla, Mohammad A.
Amer, Aliaa
Nawaz, Zafar
Abdullah, Ali S.
Al-Sabbagh, Ahmad
Kohla, Samah
Nashwan, Abdulqadir J
Yassin, Mohamed A
An uncommon case of chronic myeloid leukemia with variant cytogenetics
title An uncommon case of chronic myeloid leukemia with variant cytogenetics
title_full An uncommon case of chronic myeloid leukemia with variant cytogenetics
title_fullStr An uncommon case of chronic myeloid leukemia with variant cytogenetics
title_full_unstemmed An uncommon case of chronic myeloid leukemia with variant cytogenetics
title_short An uncommon case of chronic myeloid leukemia with variant cytogenetics
title_sort uncommon case of chronic myeloid leukemia with variant cytogenetics
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179100/
https://www.ncbi.nlm.nih.gov/pubmed/29633730
http://dx.doi.org/10.23750/abm.v89i3-S.7217
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