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Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism
Tumors are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179103/ https://www.ncbi.nlm.nih.gov/pubmed/30338239 http://dx.doi.org/10.3389/fonc.2018.00329 |
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author | Avnet, Sofia Baldini, Nicola Brisson, Lucie De Milito, Angelo Otto, Angela M. Pastoreková, Silvia Porporato, Paolo E. Szabadkai, Gyorgy Sonveaux, Pierre |
author_facet | Avnet, Sofia Baldini, Nicola Brisson, Lucie De Milito, Angelo Otto, Angela M. Pastoreková, Silvia Porporato, Paolo E. Szabadkai, Gyorgy Sonveaux, Pierre |
author_sort | Avnet, Sofia |
collection | PubMed |
description | Tumors are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can also metabolically exploit host cells. These metabolic networks are directly linked with cancer progression, treatment, resistance, and relapse. Conversely, metabolic alterations in cancer are exploited for anticancer therapy, imaging, and stratification for personalized treatments. These topics were addressed at the 4th annual meeting of the International Society of Cancer Metabolism (ISCaM) in Bertinoro, Italy, on 19–21 October 2017. |
format | Online Article Text |
id | pubmed-6179103 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-61791032018-10-18 Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism Avnet, Sofia Baldini, Nicola Brisson, Lucie De Milito, Angelo Otto, Angela M. Pastoreková, Silvia Porporato, Paolo E. Szabadkai, Gyorgy Sonveaux, Pierre Front Oncol Oncology Tumors are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can also metabolically exploit host cells. These metabolic networks are directly linked with cancer progression, treatment, resistance, and relapse. Conversely, metabolic alterations in cancer are exploited for anticancer therapy, imaging, and stratification for personalized treatments. These topics were addressed at the 4th annual meeting of the International Society of Cancer Metabolism (ISCaM) in Bertinoro, Italy, on 19–21 October 2017. Frontiers Media S.A. 2018-10-03 /pmc/articles/PMC6179103/ /pubmed/30338239 http://dx.doi.org/10.3389/fonc.2018.00329 Text en Copyright © 2018 Avnet, Baldini, Brisson, De Milito, Otto, Pastoreková, Porporato, Szabadkai and Sonveaux. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Avnet, Sofia Baldini, Nicola Brisson, Lucie De Milito, Angelo Otto, Angela M. Pastoreková, Silvia Porporato, Paolo E. Szabadkai, Gyorgy Sonveaux, Pierre Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism |
title | Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism |
title_full | Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism |
title_fullStr | Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism |
title_full_unstemmed | Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism |
title_short | Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism |
title_sort | annual meeting of the international society of cancer metabolism (iscam): cancer metabolism |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179103/ https://www.ncbi.nlm.nih.gov/pubmed/30338239 http://dx.doi.org/10.3389/fonc.2018.00329 |
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