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Relationship Between Human mutL Homolog 1 (hMLH1) Hypermethylation and Colorectal Cancer: A Meta-Analysis

BACKGROUND: Hypermethylation of CpG islands in gene promoter regions is an important mechanism of gene inactivation in cancers. Promoter hypermethylation of human mutL homolog 1 (hMLH1) has been implicated in a subset of colorectal cancers that show microsatellite instability (MSI), while the connec...

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Detalles Bibliográficos
Autores principales:	Zhang, Hui-Feng, Lu, You-Wang, Xie, Zhen-Rong, Wang, Kun-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Meta-Analysis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179171/ https://www.ncbi.nlm.nih.gov/pubmed/28635682 http://dx.doi.org/10.12659/MSM.895643

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