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Interaction of the Warsaw breakage syndrome DNA helicase DDX11 with the replication fork-protection factor Timeless promotes sister chromatid cohesion

Establishment of sister chromatid cohesion is coupled to DNA replication, but the underlying molecular mechanisms are incompletely understood. DDX11 (also named ChlR1) is a super-family 2 Fe-S cluster-containing DNA helicase implicated in Warsaw breakage syndrome (WABS). Herein, we examined the role...

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Detalles Bibliográficos
Autores principales: Cortone, Giuseppe, Zheng, Ge, Pensieri, Pasquale, Chiappetta, Viviana, Tatè, Rosarita, Malacaria, Eva, Pichierri, Pietro, Yu, Hongtao, Pisani, Francesca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179184/
https://www.ncbi.nlm.nih.gov/pubmed/30303954
http://dx.doi.org/10.1371/journal.pgen.1007622

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