Cargando…

Transcriptomics reveal potential vaccine antigens and a drastic increase of upregulated genes during Theileria parva development from arthropod to bovine infective stages

Theileria parva is a protozoan parasite transmitted by the brown ear tick Rhipicephalus appendiculatus that causes East Coast fever (ECF) in cattle, resulting in substantial economic losses in the regions of southern, eastern and central Africa. The schizont form of the parasite transforms the bovin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tonui, Triza, Corredor-Moreno, Pilar, Kanduma, Esther, Njuguna, Joyce, Njahira, Moses N., Nyanjom, Steven G., Silva, Joana C., Djikeng, Appolinaire, Pelle, Roger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179218/ https://www.ncbi.nlm.nih.gov/pubmed/30303978 http://dx.doi.org/10.1371/journal.pone.0204047

Ejemplares similares

Comparative Transcriptomics of the Bovine Apicomplexan Parasite Theileria parva Developmental Stages Reveals Massive Gene Expression Variation and Potential Vaccine Antigens
por: Atchou, Kodzo, et al.
Publicado: (2020)

Characterization of the Theileria parva sporozoite proteome
por: Nyagwange, James, et al.
Publicado: (2018)

Genetic and antigenic variation of the bovine tick-borne pathogen Theileria parva in the Great Lakes region of Central Africa
por: Amzati, Gaston S., et al.
Publicado: (2019)

Cis regulatory motifs and antisense transcriptional control in the apicomplexan Theileria parva
por: Tretina, Kyle, et al.
Publicado: (2016)

First detection of Theileria parva in cattle from Cameroon in the absence of the main tick vector Rhipicephalus appendiculatus
por: Silatsa, Barberine A., et al.
Publicado: (2020)

Prevalence of tick-transmitted pathogens in cattle reveals that Theileria parva, Babesia bigemina and Anaplasma marginale are endemic in Burundi
por: Nyabongo, Lionel, et al.
Publicado: (2021)

Approaches to vaccination against Theileria parva and Theileria annulata
por: Nene, V., et al.
Publicado: (2016)

Analysis of the Role of TpUB05 Antigen from Theileria parva in Immune Responses to Malaria in Humans Compared to Its Homologue in Plasmodium falciparum the UB05 Antigen
por: Dinga, Jerome Nyhalah, et al.
Publicado: (2020)

Changes in the Molecular and Functional Phenotype of Bovine Monocytes during Theileria parva Infection
por: Bastos, Reginaldo G., et al.
Publicado: (2019)

Two Theileria parva CD8 T Cell Antigen Genes Are More Variable in Buffalo than Cattle Parasites, but Differ in Pattern of Sequence Diversity
por: Pelle, Roger, et al.
Publicado: (2011)

Transcriptional profiling of inflammatory cytokine genes in African buffaloes (Syncerus caffer) infected with Theileria parva
por: Okagawa, Tomohiro, et al.
Publicado: (2012)

In silico identification of Theileria parva surface proteins
por: Gurav, Nitisha, et al.
Publicado: (2022)

The entry of Theileria parva sporozoites into bovine lymphocytes: evidence for MHC class I involvement
Publicado: (1991)

Antibodies to in silico selected GPI-anchored Theileria parva proteins neutralize sporozoite infection in vitro
por: Nyagwange, James, et al.
Publicado: (2018)

Genetic markers associated with resistance to beta-lactam and quinolone antimicrobials in non-typhoidal Salmonella isolates from humans and animals in central Ethiopia
por: Eguale, Tadesse, et al.
Publicado: (2017)

Genes encoding two Theileria parva antigens recognized by CD8(+) T-cells exhibit sequence diversity in South Sudanese cattle populations but the majority of alleles are similar to the Muguga component of the live vaccine cocktail
por: Salih, Diaeldin A., et al.
Publicado: (2017)

South African Buffalo-Derived Theileria parva Is Distinct From Other Buffalo and Cattle-Derived T. parva
por: Maboko, Boitumelo B., et al.
Publicado: (2021)

Properties of non-coding DNA and identification of putative cis-regulatory elements in Theileria parva
por: Guo, Xiang, et al.
Publicado: (2008)

Live immunisation against Theileria parva: containing or spreading the disease?
por: McKeever, Declan J.
Publicado: (2007)

Anti-parasitic benzoxaboroles are ineffective against Theileria parva in vitro
por: Steketee, Pieter C., et al.
Publicado: (2023)

TparvaDB: a database to support Theileria parva vaccine development
por: Visendi, Paul, et al.
Publicado: (2011)

Construction of a genetic map for Theileria parva: Identification of hotspots of recombination
por: Katzer, Frank, et al.
Publicado: (2011)

Genotypic diversity, a survival strategy for the apicomplexan parasite Theileria parva
por: Katzer, F., et al.
Publicado: (2010)

Theileria parva antigens recognized by CD8+ T cells show varying degrees of diversity in buffalo-derived infected cell lines
por: Sitt, Tatjana, et al.
Publicado: (2018)

High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing
por: Henson, Sonal, et al.
Publicado: (2012)

Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva
por: Hemmink, Johanneke D., et al.
Publicado: (2016)

Absolute Quantification of the Host-To-Parasite DNA Ratio in Theileria parva-Infected Lymphocyte Cell Lines
por: Gotia, Hanzel T., et al.
Publicado: (2016)

TpUB05, a Homologue of the Immunodominant Plasmodium falciparum Protein UB05, Is a Marker of Protective Immune Responses in Cattle Experimentally Vaccinated against East Coast Fever
por: Dinga, Jerome Nyhalah, et al.
Publicado: (2015)

Analysis of the transcriptome of the protozoan Theileria parva using MPSS reveals that the majority of genes are transcriptionally active in the schizont stage
por: Bishop, Richard, et al.
Publicado: (2005)

Expression Analysis of the Theileria parva Subtelomere-Encoded Variable Secreted Protein Gene Family
por: Schmuckli-Maurer, Jacqueline, et al.
Publicado: (2009)

Epidemiology of East Coast fever (Theileria parva infection) in Kenya: past, present and the future
por: Gachohi, John, et al.
Publicado: (2012)

Population genetic analysis and sub-structuring of Theileria parva in the northern and eastern parts of Zambia
por: Muleya, Walter, et al.
Publicado: (2012)

Exposure of vaccinated and naive cattle to natural challenge from buffalo-derived Theileria parva
por: Sitt, Tatjana, et al.
Publicado: (2015)

Molecular and Antigenic Properties of Mammalian Cell-Expressed Theileria parva Antigen Tp9
por: Bastos, Reginaldo G., et al.
Publicado: (2019)

Development of a Potential Yeast-Based Vaccine Platform for Theileria parva Infection in Cattle
por: Goh, Shan, et al.
Publicado: (2021)

Re-annotation of the Theileria parva genome refines 53% of the proteome and uncovers essential components of N-glycosylation, a conserved pathway in many organisms
por: Tretina, Kyle, et al.
Publicado: (2020)

Microbial Community Structure and Diversity in an Integrated System of Anaerobic-Aerobic Reactors and a Constructed Wetland for the Treatment of Tannery Wastewater in Modjo, Ethiopia
por: Desta, Adey Feleke, et al.
Publicado: (2014)

Correction: Microbial Community Structure and Diversity in an Integrated System of Anaerobic-Aerobic Reactors and a Constructed Wetland for the Treatment of Tannery Wastewater in Modjo, Ethiopia
por: Desta, Adey Feleke, et al.
Publicado: (2015)

Ancient diversity and geographical sub-structuring in African buffalo Theileria parva populations revealed through metagenetic analysis of antigen-encoding loci()
por: Hemmink, Johanneke D., et al.
Publicado: (2018)

The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence
por: Norling, Martin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_krf1efredqfsqa26u76br46bu9