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Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults
New neurons continue to be born in the subgranular zone (SGZ) in the dentate gyrus (DG) of the adult mammalian hippocampus(1–5). This process has been linked to learning and memory, stress and exercise, and is thought to be altered in neurological disease(6–10). In humans, some studies suggest that...
Autores principales: | Sorrells, Shawn F., Paredes, Mercedes F., Cebrian-Silla, Arantxa, Sandoval, Kadellyn, Qi, Dashi, Kelley, Kevin W., James, David, Mayer, Simone, Chang, Julia, Auguste, Kurtis I., Chang, Edward, Gutierrez Martin, Antonio J., Kriegstein, Arnold R., Mathern, Gary W., Oldham, Michael C., Huang, Eric J., Garcia-Verdugo, Jose Manuel, Yang, Zhengang, Alvarez-Buylla, Arturo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179355/ https://www.ncbi.nlm.nih.gov/pubmed/29513649 http://dx.doi.org/10.1038/nature25975 |
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