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Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling

Developmental neuronal remodeling is an evolutionarily conserved mechanism required for precise wiring of nervous systems. Despite its fundamental role in neurodevelopment and proposed contribution to various neuropsychiatric disorders, the underlying mechanisms are largely unknown. Here, we uncover...

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Detalles Bibliográficos
Autores principales: Alyagor, Idan, Berkun, Victoria, Keren-Shaul, Hadas, Marmor-Kollet, Neta, David, Eyal, Mayseless, Oded, Issman-Zecharya, Noa, Amit, Ido, Schuldiner, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179959/
https://www.ncbi.nlm.nih.gov/pubmed/30300589
http://dx.doi.org/10.1016/j.devcel.2018.09.013