Cargando…

Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling

Developmental neuronal remodeling is an evolutionarily conserved mechanism required for precise wiring of nervous systems. Despite its fundamental role in neurodevelopment and proposed contribution to various neuropsychiatric disorders, the underlying mechanisms are largely unknown. Here, we uncover...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alyagor, Idan, Berkun, Victoria, Keren-Shaul, Hadas, Marmor-Kollet, Neta, David, Eyal, Mayseless, Oded, Issman-Zecharya, Noa, Amit, Ido, Schuldiner, Oren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179959/ https://www.ncbi.nlm.nih.gov/pubmed/30300589 http://dx.doi.org/10.1016/j.devcel.2018.09.013

Ejemplares similares

Glial Derived TGF-β Instructs Axon Midline Stopping
por: Marmor-Kollet, Neta, et al.
Publicado: (2019)

Actin-dependent astrocytic infiltration is a key step for axon defasciculation during remodeling
por: Marmor-Kollet, Neta, et al.
Publicado: (2023)

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila
por: Meltzer, Hagar, et al.
Publicado: (2019)

Long term ex vivo culturing of Drosophila brain as a method to live image pupal brains: insights into the cellular mechanisms of neuronal remodeling
por: Rabinovich, Dana, et al.
Publicado: (2015)

Developmental axon regrowth and primary neuron sprouting utilize distinct actin elongation factors
por: Yaniv, Shiri P., et al.
Publicado: (2020)

Neuronal excitability as a regulator of circuit remodeling
por: Mayseless, Oded, et al.
Publicado: (2023)

Pruning deficits of the developing Drosophila mushroom body result in mild impairment in associative odour learning and cause hyperactivity
por: Poppinga, Haiko, et al.
Publicado: (2022)

Meso-seq for in-depth transcriptomics in ultra-low amounts of FACS-purified neuronal nuclei
por: Apelblat, Daniella, et al.
Publicado: (2022)

Digital cell quantification identifies global immune cell dynamics during influenza infection
por: Altboum, Zeev, et al.
Publicado: (2014)

PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model
por: Rosenzweig, Neta, et al.
Publicado: (2019)

An efficient analytical reduction of detailed nonlinear neuron models
por: Amsalem, Oren, et al.
Publicado: (2020)

Pre-mRNA Splicing Is a Determinant of Nucleosome Organization
por: Keren-Shaul, Hadas, et al.
Publicado: (2013)

Pre-mRNA splicing is a determinant of nucleosome organization
por: Keren-Shaul, Hadas, et al.
Publicado: (2013)

Integration of scRNA-Seq and bulk RNA-Seq uncover perturbed immune cell types and pathways of Kawasaki disease
por: Cao, Naixin, et al.
Publicado: (2023)

Systematic Approaches to Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins
por: Mark, Maayan, et al.
Publicado: (2023)

Chemically programmable bacterial probes for the recognition of cell surface proteins
por: Prasad, Pragati K., et al.
Publicado: (2023)

Uncovering the secrets of hidden twists
por: Hod, Oded, et al.
Publicado: (2023)

Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay
por: Rosenthal, Mira, et al.
Publicado: (2020)

Single-cell RNA-seq uncovers dynamic processes orchestrated by RNA-binding protein DDX43 in chromatin remodeling during spermiogenesis
por: Tan, Huanhuan, et al.
Publicado: (2023)

Extended phylogenetic analysis of a new Israeli isolate of Brevicoryne brassicae virus (BrBV-IL) suggests taxonomic revision of the genus Iflavirus
por: Luria, Neta, et al.
Publicado: (2016)

Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis
por: Goldman, Omer, et al.
Publicado: (2023)

A Similarity-Based Method for Predicting Enzymatic Functions in Yeast Uncovers a New AMP Hydrolase
por: Cohen, Nir, et al.
Publicado: (2022)

The association between creativity and 7R polymorphism in the dopamine receptor D4 gene (DRD4)
por: Mayseless, Naama, et al.
Publicado: (2013)

Active suppression of a leaf meristem orchestrates determinate leaf growth
por: Alvarez, John Paul, et al.
Publicado: (2016)

Perturbations in Histidine Biosynthesis Uncover Robustness in the Metabolic Network of Salmonella enterica
por: Koenigsknecht, Mark J., et al.
Publicado: (2012)

Lettuce Chlorosis Virus Disease: A New Threat to Cannabis Production
por: Hadad, Lior, et al.
Publicado: (2019)

VISUAL-CC system uncovers the role of GSK3 as an orchestrator of vascular cell type ratio in plants
por: Tamaki, Takayuki, et al.
Publicado: (2020)

DestVI identifies continuums of cell types in spatial transcriptomics data
por: Lopez, Romain, et al.
Publicado: (2022)

Expertise in Musical Improvisation and Creativity: The Mediation of Idea Evaluation
por: Kleinmintz, Oded M., et al.
Publicado: (2014)

Attention Matters: How Orchestrating Attention May Relate to Classroom Learning
por: Keller, Arielle S., et al.
Publicado: (2020)

Uncovering foveal crowding?
por: Lev, Maria, et al.
Publicado: (2014)

Biased distance estimation in social anxiety disorder: A new avenue for understanding avoidance behavior
por: Givon‐Benjio, Nur, et al.
Publicado: (2020)

Drug-based perturbation screen uncovers synergistic drug combinations in Burkitt lymphoma
por: Tomska, K., et al.
Publicado: (2018)

A Perturbed Ubiquitin Landscape Distinguishes Between Ubiquitin in Trafficking and in Proteolysis
por: Ziv, Inbal, et al.
Publicado: (2011)

Spatiotemporal Control of Neuronal Remodeling by Cell Adhesion Molecules: Insights From Drosophila
por: Meltzer, Hagar, et al.
Publicado: (2022)

Orchestration /
por: Forsyth, Cecil, 1870-1941
Publicado: (1982)

Orchestration.
por: Piston, Walter, 1894-1976
Publicado: (1955)

ORCHESTRATION
por: Palmer, King

Random Parametric Perturbations of Gene Regulatory Circuit Uncover State Transitions in Cell Cycle
por: Katebi, Ataur, et al.
Publicado: (2020)

Rewiring phospholipid biosynthesis reveals resilience to membrane perturbations and uncovers regulators of lipid homeostasis
por: John Peter, Arun T, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rnn61h6iq6ffljhkgbsm4pd3ss