ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea

Pathogenic gram-negatives that produce 16S ribosomal RNA methyltransferases (16S RMTases) have already been distributed all over the world. To investigate the predominance of aminoglycoside resistance associated with 16S RMTases in Korea, we collected a total of 222 amikacin resistant Gram-negative...

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Autores principales: Lee, Tae Hee, Hwang, Joo-Hee, Lee, Woo Kon, Shin, Min-Kyoung, Woo, Hye Ryun, Chung, Kyung Min, Lee, Chang-Seop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179987/
https://www.ncbi.nlm.nih.gov/pubmed/30310364
http://dx.doi.org/10.3346/jkms.2018.33.e262
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author Lee, Tae Hee
Hwang, Joo-Hee
Lee, Woo Kon
Shin, Min-Kyoung
Woo, Hye Ryun
Chung, Kyung Min
Lee, Chang-Seop
author_facet Lee, Tae Hee
Hwang, Joo-Hee
Lee, Woo Kon
Shin, Min-Kyoung
Woo, Hye Ryun
Chung, Kyung Min
Lee, Chang-Seop
author_sort Lee, Tae Hee
collection PubMed
description Pathogenic gram-negatives that produce 16S ribosomal RNA methyltransferases (16S RMTases) have already been distributed all over the world. To investigate the predominance of aminoglycoside resistance associated with 16S RMTases in Korea, we collected a total of 222 amikacin resistant Gram-negative clinical isolates from patient specimens between 1999 and 2015 from three hospital banks across Korea. ArmA and rmtB were the predominant 16S RMTase genes responsible for aminoglycoside-resistant isolates circulating in Korean community settings although only one rmtA-producing isolate was detected in 2006.
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spelling pubmed-61799872018-10-15 ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea Lee, Tae Hee Hwang, Joo-Hee Lee, Woo Kon Shin, Min-Kyoung Woo, Hye Ryun Chung, Kyung Min Lee, Chang-Seop J Korean Med Sci Brief Communication Pathogenic gram-negatives that produce 16S ribosomal RNA methyltransferases (16S RMTases) have already been distributed all over the world. To investigate the predominance of aminoglycoside resistance associated with 16S RMTases in Korea, we collected a total of 222 amikacin resistant Gram-negative clinical isolates from patient specimens between 1999 and 2015 from three hospital banks across Korea. ArmA and rmtB were the predominant 16S RMTase genes responsible for aminoglycoside-resistant isolates circulating in Korean community settings although only one rmtA-producing isolate was detected in 2006. The Korean Academy of Medical Sciences 2018-09-10 /pmc/articles/PMC6179987/ /pubmed/30310364 http://dx.doi.org/10.3346/jkms.2018.33.e262 Text en © 2018 The Korean Academy of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Lee, Tae Hee
Hwang, Joo-Hee
Lee, Woo Kon
Shin, Min-Kyoung
Woo, Hye Ryun
Chung, Kyung Min
Lee, Chang-Seop
ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea
title ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea
title_full ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea
title_fullStr ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea
title_full_unstemmed ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea
title_short ArmA and RmtB Were the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea
title_sort arma and rmtb were the predominant 16s rmtase genes responsible for aminoglycoside-resistant isolates in korea
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179987/
https://www.ncbi.nlm.nih.gov/pubmed/30310364
http://dx.doi.org/10.3346/jkms.2018.33.e262
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